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CD21兔單克隆抗體

CD21兔單克隆抗體

  • 價(jià)格¥600
  • 規(guī)格100ul
  • 貨號(hào)HKZ150133
  • 單位
  • 品牌HaoKebio

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HaoKebioHKZ150133CD21兔單克隆抗體100ul600
CD21
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
?
Catalog# ?BX50010?Clone# ?BP6015
?
Predicted?Molecular Wt:
113kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P20023

Background:
CD21 also??known?as?complement?C3d?receptor,?Epstein-Barr?virus?receptor,?and?complement?receptor?type?2?(CR2),?is?a?protein that?in?humans?is encoded?by the CR2 gene. This?protein?is?involved?in the?complement?system.?It?bindsto?iC3b?(inactive
derivative?of?C3b), C3dg,or?C3d.?B?cells?have?CR2?receptors?on?their?surfaces,?allowing?the?complement?system?to?play?a?role?in?B-?cell activation and?maturation.
It?is expressed?by follicular dendritic cells?(FDC)?and?mature?B?cells,?as well?as?by?several?types?of?epithelial?cells.
?
CD21?is?useful?in the?identification of follicular dendritic cell?matrix found?in?normal?lymph?node?and?tonsillar?tissue,?and?also?useful?in?identifying abnormal follicular dendritic cell?pattern?in?angioimmunoblastic T-cell?lymphoma?and follicular?T-cell
lymphoma.
?
?

Subcellular?location:
Membrane
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to CD21?residues?within?aa933‐C?terminal?of?CD21 was?used?as?an ????immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1. ?Barel?M, et?al.??Mol?Immunol.?1995 Apr;32(6):389-97.
?
2.?Tanner?J, et?al. ?J?Virol.?1988?Dec;62(12):4452-64.

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