一抗 抗體 試劑 OCT3/4兔單克隆抗體一抗 抗體 試劑 價(jià)格¥1000規(guī)格100ul貨號(hào)HKZ150428單位支品牌HaoKebio QQ53383090 咨詢購(gòu)買(mǎi) 產(chǎn)品介紹產(chǎn)品參數(shù)資料下載 品牌商品編碼商品名稱(chēng)規(guī)格單位單價(jià)HaoKebioHKZ150428OCT3/4兔單克隆抗體100ul支1000OCT3/4Recombinant?Rabbit?Monoclonal Antibody?Product?DatasheetCatalog# ?BX50305?Clone# ?BP6282Predicted?Molecular Wt:39kDaPurity: ??ProA?affinity?purified?IgGSpecies Cross-reactivity:HumanForm: ??LiquidApplications:IHC-PSwissprot?ID:??Q01860Background:OCT-4, also?known?as?OTF3 or?POU5F1,?is?a?member?of?the?POU?family?of?transcription?factors,?involved?in?the?regulation?of pluripotency during?normal development and?is detectable?in?embryonic?stem?and?germ?cells.?It?can?specifically?bind?to?the??octamer?motif?(5′-ATTTCAT-3′), and?it?is?critical?for?the?self-renewal?of?embryonic?stem?cells. OCT-4?is?a?key?regulator?of?self-?renewal?in embryonic stem cells;?its expression?is?potentially?correlated with?tumorigenesis?and?can?affect?some?aspects?of???tumor?behavior such as tumor?recurrence or?resistance to therapies.OCT-4?is a sensitive and specific?marker for?germ?cell?tumors.?It?is?consistently?detected?in?carcinoma?in?situ/gonadoblastoma,seminomas, germinoma, dysgerminoma, and embryonal?carcinoma?but?not?in the?differentiated?components?of?nonseminomas.An antibody to OCT-4?is?useful?in the?identification of?primary?as?well?as?metastatic?germ?cell?tumors.Subcellular?location:NucleusRecommended?Method:Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.Immunogen:Synthetic?peptide. This?information?is?proprietary to?Biolynx.Storage?Buffer:PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.Storage Conditions:-25°C?to?-18°CShipment?Instructions:Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?–?18°C. Avoid?freeze?/ thaw?cycles.Recommended?Dilution:IHC-P:?????1:100-1:200Background?References:1.?Zhang?S??et?al.?Nucleic?Acids?Res?47:4449-4461?(2019).2.?Chang?YC??et?al.?Cell?Death?Dis?11:195?(2020).Immunohistochemistry?(Formalin/PFA-fixed?paraffin-embedded?sections)?analysis of ?human seminoma?tissue?labelling?OCT3/4???with?BP6282. HKZ150428_BP6282_OCT3&4下載 暫無(wú) 說(shuō)明文檔下載說(shuō)明書(shū).pdf 上一篇: CLPS兔單克隆抗體下一篇: PTEN兔單克隆抗體 推薦 Bcl-2鼠單克隆抗體 2024年5月22日 1803 暫無(wú) 查看全文 CD8兔單克隆抗體 2024年5月20日 972 暫無(wú) 查看全文 7.5%彩色凝膠快速試劑盒 2024年9月19日 1211 【試劑組成】 詳細(xì)信息請(qǐng)參考說(shuō)明書(shū)! 無(wú) 暫無(wú) 查看全文 ROR gamma T兔單克隆抗體 2024年5月23日 804 暫無(wú) 查看全文 您好!請(qǐng)登錄 點(diǎn)擊取消回復(fù) 請(qǐng)登錄后評(píng)論 點(diǎn)擊這里取消回復(fù)。
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