一抗 抗體 試劑 PTEN兔單克隆抗體一抗 抗體 試劑 價格¥1000規(guī)格100ul貨號HKZ150429單位支品牌HaoKebio QQ53383090 咨詢購買 產(chǎn)品介紹產(chǎn)品參數(shù)資料下載 品牌商品編碼商品名稱規(guī)格單位單價HaoKebioHKZ150429PTEN兔單克隆抗體100ul支1000PTENRecombinant?Rabbit?Monoclonal Antibody?Product?DatasheetCatalog# ?BX50306?Clone# ?BP6283Predicted?Molecular Wt:54kDaPurity: ??ProA?affinity?purified?IgGSpecies Cross-reactivity:HumanForm: ??LiquidApplications:IHC-PSwissprot?ID: ??P60484Background:PTEN acts as a dual-specificity?protein?phosphatase,?dephosphorylating tyrosine-,?serine-?and?threonine-phosphorylatedproteins. Tumor suppressor, the?lipid?phosphatase activity?is critical for?its tumor?suppressor function.?Antagonizes?the?PI3K-?AKT/PKB signaling?pathway?by dephosphorylating?phosphoinositides and thereby?modulating cell?cycle?progression?and?cell??survival. The?unphosphorylated form cooperates with?MAGI2 to suppress AKT1?activation.PTEN gene?is a tumor suppressor gene that?maps to?chromosome?10q23.?PTEN?is?the?first?oncogene?with?bispecificphosphatase activity discovered?in?humans,?regulating tumour cell growth,?apoptosis?and?migration,?etc.?PTEN?is found?to?be??inactivated?in a variety of tumours, and?its?inactivation?is?due to?methylation?modifications?in?addition?to?common?mutations.High-grade endometrioid carcinomas are commonly?deficient?in?PTEN?expression.PTEN gene deletion?has also?been found?in glioblastoma,?prostate?cancer,?melanoma,?and?breast?cancer.Subcellular?location:Cytoplasm?,?NucleusRecommended?Method:Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.Immunogen:Synthetic?peptide. This?information?is?proprietary to?Biolynx.Storage?Buffer:PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.Storage Conditions:-25°C?to?-18°CShipment?Instructions:Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?-18?°C. Avoid?freeze?/ thaw?cycles.Recommended?Dilution:IHC-P:?????1:100-1:200Background?References:1.?Song?M.S. et?al.?Nature?455:813-817.2.?Stohr?N. et?al.?Genes?Dev.?26:176-189Immunohistochemical?(formalin/PFA-fixed?paraffin-?embedded?sections)?analysis of?human endometrial?carcinoma?labelled?with?PTEN?using?BP6283. HKZ150429_ BP6283_PTEN下載 暫無 說明文檔下載說明書.pdf 上一篇: OCT3/4兔單克隆抗體下一篇: PLA2R兔單克隆抗體 推薦 smooth muscle actin 兔多克隆抗體 2024年12月4日 1302 存儲說明: 以藍冰運輸。收貨后,進行分裝,并在-25°C 至-18°C 條件下儲 存。避免反復凍融。 推薦稀釋比: IHC-P: ... 查看全文 熒光單標超敏信號放大試劑盒 2024年11月8日 1465 無 查看全文 Neurofilament鼠單克隆抗體 2024年5月23日 931 暫無 查看全文 抗CD14 蛋白的抗體 2020年11月17日 754 查看全文 您好!請登錄 點擊取消回復 請登錄后評論 點擊這里取消回復。
smooth muscle actin 兔多克隆抗體 2024年12月4日 1302 存儲說明: 以藍冰運輸。收貨后,進行分裝,并在-25°C 至-18°C 條件下儲 存。避免反復凍融。 推薦稀釋比: IHC-P: ... 查看全文
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