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PSMA兔單克隆抗體

PSMA兔單克隆抗體

  • 價(jià)格¥1000
  • 規(guī)格100ul
  • 貨號(hào)HKZ150422
  • 單位
  • 品牌HaoKebio

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HaoKebioHKZ150422PSMA兔單克隆抗體100ul1000
PSMA
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50299?Clone# ?BP6276
Predicted?Molecular Wt:
84kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID:??Q04609
Background:
PSMA?is a type?II transmembrane?protein?in the?M28 family that combines?folate?hydrolase?and?N-acetylation?α?Associated??acid?dipeptidase activity.?PSMA was originally found?in the?LNCaP cell?line,?which?originated?from?lymph?node?metastasis?of?prostate cancer.
Research studies?have shown that?PSMA?is a well-defined?marker for?prostate?cancer?and?is?also?expressed?in?other?tissues?such as the?kidney,?liver, and?bladder.
PSMA?is?used as a?diagnostic and?prognostic?indicator of?prostate?cancer,?and?as?a?possible?marker?for?various?neurological?disorders such as schizophrenia, Alzheimer disease?and?Huntington?disease.
Subcellular?location:
Cytoplasm&Membrane
Recommended?Method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide. This?information?is?proprietary to?Biolynx.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage Conditions:
-25°C?to?-18°C
Shipment?Instructions:
Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?-18?°C. Avoid?freeze?/ thaw?cycles.
Recommended?Dilution:
IHC-P:?????1:100-1:200
Background?References:
1. ?Mease,?R.C. ?(2013) Curr?Top?Med?Chem?13,?951-62.
2. ?Frigerio,?B.?(2013)?Eur?J?Cancer?49,?2223-32.
Immunohistochemistry?(Formalin/PFA-fixed?paraffin-embedded?sections)?analysis of ?human?prostate?labelling?PSMA with
BP6276.

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