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Nestin兔單克隆抗體

Nestin兔單克隆抗體

  • 價格¥2200
  • 規(guī)格100ul
  • 貨號HKZ150421
  • 單位
  • 品牌HaoKebio

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HaoKebioHKZ150421Nestin兔單克隆抗體100ul2200
Nestin
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50298?Clone# ?BP6275
Predicted?Molecular Wt:
177kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P48681
Background:
Nestin?is an?intermediate filament family?member?protein that?is structurally?related to the?neurofilament?proteins.?It?is?highly?expressed?in the developing?brain, where?it?may?help to?regulate cell structure?and?intracellular?processes?required?for?neural??cell division?and?migration.
Research studies?have shown that expression of?nestin?is?also?found?in?cells?from?various?nervous?system?tumors,?including?gliomas,?neuroblastomas, astrocytomas, and?it?is generally accepted?as?a?marker?for?neural?cancer?stem?cells.
Nestin expression?is significantly?increased?in?melanoma and correlated?with?more?advanced?stages?of the?disease.
Subcellular?location:
Cytoplasm
Recommended?Method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide. This?information?is?proprietary to?Biolynx.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage Conditions:
-25°C?to?-18°C
Shipment?Instructions:
Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?–?18°C. Avoid?freeze?/ thaw?cycles.
Recommended?Dilution:
IHC-P:?????1:100-1:200
Background?References:
1.?Giliarov, A.V.?(2007)?Morfologiia?131, 85-90.
2.?Gilyarov, A.V.?(2008)?Neurosci?Behav?Physiol?38,?165-9.
Immunohistochemistry?(Formalin/PFA-fixed?paraffin-embedded?sections)?analysis?of??human?tonsil?labelling?Nestin?with?BP6275.

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