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TLE1兔單克隆抗體

TLE1兔單克隆抗體

  • 價(jià)格￥1000
  • 規(guī)格100ul
  • 貨號HKZ150369
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150369TLE1兔單克隆抗體100ul支1000
TLE1
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50246?Clone# ?BP6223
Predicted?Molecular Wt:
83kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID:??Q04724
Background:
TLE1?binds to a?number of transcription factors.?It?inhibits?NF-kappa-B-regulated gene?expression,also?inhibits the
transcriptional activation?mediated?by?FOXA2, and?by CTNNB1 and?TCF?family?members?in?Wnt?signaling.?It?enhances?FOXG1/BF-1- and?HES1-mediated?transcriptional?repression.
TLE1?is wildly expressed?in?normal and?cancer tissues.???TLE1?is generally?use for diagnosis of synovial?sarcoma.
Subcellular?location:
Nucleus
Recommended?Method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Full?length?protein corresponding to?Human TLE1.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage Conditions:
-25°C?to?-18°C
Shipment?Instructions:
Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?–?18°C. Avoid?freeze?/ thaw?cycles.
Recommended?Dilution:
IHC-P:?????1:100-1:200
Background?References:
1.?Tetsuka?T.,?Uranishi?H.,?Imai?H.,?Ono?T., Sonta?S. J.?Biol.?Chem.?275:4383-4390(2000)
Immunohistochemistry?(Formalin/PFA-fixed?paraffin-
embedded?sections)?analysis of synovial sarcoma?labelling?TLE1 with?BP6223.

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