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Synaptophysin兔單克隆抗體

Synaptophysin克隆抗體

  • 價格￥600
  • 規(guī)格100ul
  • 貨號HKZ150171
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150171Synaptophysin兔單克隆抗體100ul支600
Synaptophysin
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# BX50048?Clone# ?BP6053
Predicted?Molecular Wt:
34kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P08247
Background:
Synaptophysin, also?known as the?major synaptic vesicle?protein?p38,?is?a?protein that?in?humans?is?encoded?by?the?SYP?gene.?The?exact function of the?protein?is?unknown:?it?interacts with the essential synaptic?vesicle?proteinsynaptobrevin,?but?when?the
synaptophysin gene?is experimentally?inactivated?in animals, they still?develop?and function?normally.
Synaptophysin?reacts with?neuroendocrine cells of?human adrenal?medulla, carotid?body,?skin,?pituitary,?thyroid,?lung,?pancreas,?and gastrointestinal?mucosa. This antibody?identifies?normal?neuroendocrine cells and?neuroendocrine?neoplasms.
Synaptophysin?is expressed?independently of other?neuronal differentiation?markers?and?may?be?used?as?a?differentiation?marker?in tumor?diagnosis.
Subcellular?location:
Cytoplasm
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to?synaptophysin
residues?within?aa213-313 of?synaptophysin?was?used as an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Wiedenmann?B,?et.al.?Proc?Natl?Acad?Sci?U?S?A.?1986?May;83(10):3500-4.
2.?Quinn?B. Am?J?Surg?Pathol.?1998?May;22(5):550-6.
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections analysis?of
glioma tissue?labelling?synaptophysin with
BP6053.?Heat?mediated antigen?retrieval?was
performed?using
Tris/EDTA?buffer?pH?9.0

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