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L1CAM兔單克隆抗體

L1CAM兔單克隆抗體

  • 價(jià)格¥2200
  • 規(guī)格100ul
  • 貨號(hào)HKZ150403
  • 單位
  • 品牌HaoKebio

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HaoKebioHKZ150403L1CAM兔單克隆抗體100ul2200
L1CAM
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50280?Clone# ?BP6257
Predicted?Molecular Wt:
140kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P32004
Background:
L1CAM,a?neural cell adhesion?molecule which?is?involved?in the dynamics?of?cell?adhesion?and?in the?generation?of
transmembrane signals at tyrosine?kinase?receptors.?During?brain development,?L1CAM?is critical?in?multiple?processes,
including?neuronal?migration, axonal growth and fasciculation, and?synaptogenesis.?In?the?mature?brain,?L1CAM?plays?a?role?in the dynamics of?neuronal structure and?function,?including?synaptic?plasticity.
L1CAM’s cytoplasmic expression?mainly?in?CNS,?PNS and distal?renal?tubules.
L1CAM?has?become a?marker for evaluating the?malignancy and?prognosis?of?ovarian?cancer,?endometrial?cancer,?melanoma?and other?tumors.
Subcellular?location:
Cytoplasm
Recommended?Method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide. This?information?is?proprietary to?Biolynx.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage Conditions:
-25°C?to?-18°C
Shipment?Instructions:
Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?–?18°C. Avoid?freeze?/ thaw?cycles.
Recommended?Dilution:
IHC-P:?????1:100-1:200
Background?References:
Sch?fer,?M.?K.?E., et?al.?Neurobiology?of?Disease,?40(1),?222–237.
Immunohistochemistry?(Formalin/PFA-fixed?paraffin-
embedded?sections)?analysis of ?human?Kidney?labelling?L1CAM?with?BP6257.

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