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CD63兔單克隆抗體

CD63兔單克隆抗體

  • 價格￥1000
  • 規(guī)格100ul
  • 貨號HKZ150417
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150417CD63兔單克隆抗體100ul支1000
CD63
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50294?Clone# ?BP6271
Predicted?Molecular Wt:
26kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P08962
Background:
CD63?Functions as cell surface?receptor for TIMP1?and?plays a?role?in?the?activation?of?cellular?signaling?cascades.?It?plays?a
role?in the activation of?ITGB1 and?integrin?signaling,?leading to?the?activation?of AKT,?FAK/PTK2?and?MAP?kinases.?It?promotes
cell survival,?reorganization of the actin cytoskeleton,?cell?adhesion,?spreading?and?migration.?It?also?plays?a?role?in?intracellular vesicular transport?processes.
CD63?is weakly expressed on?B and T?cells?and?granulocytes.?It’s?also?expressed?in?bronchial?glands,?neural tissue?(brain?white?matter and?peripheral?nerves),?nevi, salivary?glands, smooth?muscle?and?synovial?lining?cells.
CD63?is a?marker of?melanoma?(although?non-specific) and?melanocytic tumors.
Subcellular?location:
Membrane and?cytoplasm
Recommended?Method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Recombinant?protein fragment of CD63 was?used?as?an?immunogen. This?information?is?proprietary to?Biolynx.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage Conditions:
-25°C?to?-18°C
Shipment?Instructions:
Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?–?18°C. Avoid?freeze?/ thaw?cycles.
Recommended?Dilution:
IHC-P:?????1:100-1:200
Background?References:
1. ?PMID:?16917503
2. ?PMID:?19640571
Immunohistochemistry?(Formalin/PFA-fixed?paraffin-embedded?????sections)?analysis?of??human?prostate?labelling?CD63 with?BP6271

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