一抗 抗體 試劑 p16鼠單克隆抗體一抗 抗體 試劑 價(jià)格¥1000規(guī)格100ul貨號(hào)HKZ150384單位支品牌HaoKebio QQ53383090 咨詢購(gòu)買 產(chǎn)品介紹產(chǎn)品參數(shù)資料下載 品牌商品編碼商品名稱規(guī)格單位單價(jià)HaoKebioHKZ150384p16鼠單克隆抗體100ul支1000p16Mouse?Monoclonal Antibody?Product?DatasheetCatalog# ?BX50261???Clone# ?BPM6238Predicted?Molecular Wt:17kDaPurity: ??ProG?affinity?purified?IgGSpecies Cross-reactivity:HumanForm: ??LiquidApplications:IHC-PSwissprot?ID: ??P42771Background:The?progression of cells through the cell cycle?is?regulated?by?a?family?of?protein?kinases?known?as?cyclin-dependent?kinases?(Cdks). The sequential activation of individual?members?of this?family?and?their?consequent?phosphorylation?of?criticalsubstrates?promotes orderly?progression through the cell cycle.??Moreover, the?gene?encoding?p16?INK4A?exhibits?a?high?frequency of?homozygous deletions and?point?mutations?in established?human?tumor?cell?lines.p16?INK4A?expression?is?commonly?inhibited?by?lack?of?stress?and?is?thought?to?promote?cellular?senescence.?And?p16 INK4A?expression?is a commonly?used cellular?marker of?senescence.p16?INK4A?protein expression?is?normally?altered?in?human?cancer cells, and?its?high expression?can?be?used?as?a?predictive?biomarker?in cervical cancer?cells.Subcellular?location:NucluesRecommended?Method:Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.Immunogen:Full?length?recombinant?p16?INK4A?of?human?origin was?used as?an?immunogen.Storage?Buffer:PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.Storage Conditions:-25°C?to?-18°CShipment?Instructions:Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?-18?°C. Avoid?freeze?/ thaw?cycles.Recommended?Dilution:IHC-P:?????1:100-1:200Background?References:1. ?Romagosa,?C. et?al.?(2011) Oncogene?30,?2087-97.2. ?LaPak,?K.M. and?Burd,?C.E.?(2014)?Mol?Cancer?Res?12,?167-83.Immunohistochemistry?(Formalin/PFA-fixed?paraffin-embedded?sections)?analysis of cervical?intraepithelial?neoplasias ?(CIN)labelling?p16 with?BPM6238.? HKZ150384_BPM6238_p16下載 暫無(wú) 說(shuō)明文檔下載說(shuō)明書(shū).pdf 上一篇: Procalc itonin兔單克隆抗體下一篇: CXCR5兔單克隆抗體 推薦 熒光五標(biāo)信號(hào)放大試劑盒(石蠟切片適用) 2024年12月10日 1835 查看全文 PSA兔單克隆抗體 2024年5月21日 1012 暫無(wú) 查看全文 增強(qiáng)型蛋白酶抑制劑混合液(EDTA-Free,100X) 2024年9月18日 2721 服務(wù)介紹: 增強(qiáng)型蛋白酶抑制劑混合液(Protease Inhibitor Cocktail)是多種蛋白酶抑制劑混合物組成的一款高效、廣譜的抑制劑混合... 查看全文 MUM1兔單克隆抗體 2024年5月23日 1039 暫無(wú) 查看全文 您好!請(qǐng)登錄 點(diǎn)擊取消回復(fù) 請(qǐng)登錄后評(píng)論 點(diǎn)擊這里取消回復(fù)。
增強(qiáng)型蛋白酶抑制劑混合液(EDTA-Free,100X) 2024年9月18日 2721 服務(wù)介紹: 增強(qiáng)型蛋白酶抑制劑混合液(Protease Inhibitor Cocktail)是多種蛋白酶抑制劑混合物組成的一款高效、廣譜的抑制劑混合... 查看全文
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