一抗 抗體 試劑 VEGF兔單克隆抗體一抗 抗體 試劑 價格¥1000規(guī)格100ul貨號HKZ150359單位支品牌HaoKebio QQ53383090 咨詢購買 產(chǎn)品介紹產(chǎn)品參數(shù)資料下載 品牌商品編碼商品名稱規(guī)格單位單價HaoKebioHKZ150359VEGF兔單克隆抗體100ul支1000VEGFRecombinant?Rabbit?Monoclonal Antibody?Product?DatasheetCatalog# ?BX50236?Clone# ?BP6213Predicted?Molecular Wt:24kDaPurity: ??ProA?affinity?purified?IgGSpecies Cross-reactivity:HumanForm: ??LiquidApplications:IHC-PSwissprot?ID: ??P15692Background:Vascular?Endothelial Growth?Factor A?(VEGF-A; formerly VEGF)?belongs to the VEGF/PDGF family?of growth factors?that?play?a?critical?role?in?promoting vascular development. VEGF-A?is?primarily?known for?its function?in?promoting angiogenesis, theprocess?by which?new?bloodvessels are sprouted from?pre-existing?bloodvessels. VEGF-A?has eight?isoforms,?derived?fromdifferentially spliced?mRNA variants encoded?by the VEGF-A gene. All?isoforms?contain?a?conserved?receptor?binding?domain,?but differ?in their C-terminal domains that?regulate?binding to?components?in?the?extracellular?matrix.?VEGF-A?is?secreted?by???multiple cell types,?including fibroblasts,?macrophages and some tumor?cells.?Binding?of VEGF-A to?its?cognate?receptors(VEGFR2 and to a?lesser extent VEGFR1)?on?the?endothelial?cell?surface?activates the?receptor?and?initiates?downstream?signaling,?resulting?in endothelial cell?proliferation, survival,?migration, and?changes to?vascular?permeability,?all?crucial??processes for angiogenesis.Subcellular?location:CytoplasmRecommended?method:Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.Immunogen:Recombinant?protein fragment of?human VEGF.PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.Storage conditions:-25°C?to?-18°CStorage instructions:Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.Recommended?Dilutions:IHC-P:?????1:100-1:200Background?References:1.?Chaudhry?IH, O’Donovan?DG, et?al.?(2001)?.?Histopathology?91:409–415.2. ?Boer?K, Troost?D, Spliet?WGM, et?al.(2008)?.?Acta?Neuropathol?115:?683–696.Immunohistochemistry(Formalin/PFA-fixed?paraffin-embedded?sections)?analysis of?human?liver?carcinoma tissuelabelling?VEGF?with?BP6213.Heat?mediated?antigen?retrieval?was?performed?using Tris/EDTA??buffer?pH?9.0 HKZ150359_BP6213_VEGF下載 暫無 說明文檔下載說明書.pdf 上一篇: BCMA兔單克隆抗體下一篇: Bcl-6兔單克隆抗體 推薦 SDS-PAGE凝膠制備試劑盒 2024年9月19日 1261 【試劑組成】 詳細(xì)信息請參考說明書! 無 暫無 查看全文 PLA2R兔單克隆抗體 2024年5月24日 1093 查看全文 Trans RNA 轉(zhuǎn)染試劑 2024年11月26日 2793 暫無 查看全文 RIPA裂解液(強(qiáng)) 2024年9月14日 2471 暫無 查看全文 您好!請登錄 點(diǎn)擊取消回復(fù) 請登錄后評論 點(diǎn)擊這里取消回復(fù)。
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