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- 價格¥600
- 規(guī)格100ul
- 貨號HKZ150312
- 單位支
- 品牌HaoKebio
產(chǎn)品介紹
產(chǎn)品參數(shù)
資料下載
品牌 | 商品編碼 | 商品名稱 | 規(guī)格 | 單位 | 單價 |
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HaoKebio | HKZ150312 | O lig2兔單克隆抗體 | 100ul | 支 | 600 |
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Olig2
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50189?Clone# ?BP6167
Predicted?Molecular Wt:
32kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID:??Q13516
Background:
Olig2, a?basic?helix–loop–helix transcription factor,?is?involved?in oligodendroglial specification.?Olig2?expression?has?been
reported?in?most glial tumors, such asoligodendrogliomas and?astrocytomas. Although?more?than?half?of?glioblastomas?are
positive for?Olig2, expression?is very weak?in terms of?both?percentage?of?labeled?cells?and?intensity.?No?Olig2?expression?has????been found?in the?non-glial tumors?including?neuroepithelial tumors, ependymomas, subependymomas,?medulloblastomas,?????and?nonneuroepithelial tumors, such as CNS?lymphomas,?meningiomas, schwannomas,?atypical teratoid/rhabdoid?tumor,?and?haemangioblastomas. Compared to the strong staining seen?in?glioma?samples,?a?weak?expression?is?observed?in?non-tumoral??brain tissue.
Subcellular?location:
Nucleus
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to?residues?in?Human?Olig2 was?used as?an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Shou?JW??etal.?Front?Cell?Neurosci?13:395?(2019).
2.?Cho?KHT??etal. Sci?Rep?10:6904?(2020).
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections)?analysis
of??human?brain tissue?labelling Olig2?with
BP6167.?Heat?mediated antigen?retrieval was
performed?using
Tris/EDTA?buffer?pH?9.0
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