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FOXP3兔單克隆抗體

FOXP3兔單克隆抗體

  • 價(jià)格￥2200
  • 規(guī)格100ul
  • 貨號(hào)HKZ150311
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150311FOXP3兔單克隆抗體100ul支2200
FOXP3
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50188?Clone# ?BP6166
Predicted?Molecular Wt:
47kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID:??Q9BZS1
Background:
Forkhead?box?(Fox)?proteins area family of evolutionarily conserved?transcription?factors?containing?a?sequence?known?as?Forkhead?box or winged?helix?DNA?binding domain. The?human genome?contains 43?Fox?proteins?that?are?divided?into
subfamilies. The?FoxP subfamily?has four?members,?FoxP1 –?FoxP4, which are?broadly?expressed?and?play?important?roles?in
organ?development,?immune?response, and cancer?pathogenesis.?FoxP?proteins?usually function as transcriptional?repressors.?FOXP3?is expressed?in?activated T?lymphocytes?in tonsil?in adult, T cell?leukemia?or?lymphoma.
Subcellular?location:
Nucleus
Recommended?Method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Recombinant fragment corresponding to?human?FOXP3 was?used as?an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage Conditions:
-25°C?to?-18°C
Shipment?Instructions:
Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?-18?°C. Avoid?freeze?/ thaw?cycles.
Recommended?Dilution:
IHC-P:?????1:100-1:200
Background?References:
1.?Zuo, T. et?al.?(2007)?Cell?129,?1275-86.
2.?Wang,?L.?et?al.?(2009) Cancer?Cell?16,?336-46.
Immunohistochemistry?(Formalin/PFA-fixed?paraffin-
embedded?sections)?analysis of tonsil?labelling?FOXP3 with?BP6166.

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