一抗 抗體 試劑 HER2兔單克隆抗體一抗 抗體 試劑 價(jià)格¥1000規(guī)格100ul貨號(hào)HKZ150138單位支品牌HaoKebio QQ53383090 咨詢購(gòu)買 產(chǎn)品介紹產(chǎn)品參數(shù)資料下載 品牌商品編碼商品名稱規(guī)格單位單價(jià)HaoKebioHKZ150138HER2兔單克隆抗體100ul支1000HER-2Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet?Catalog# ?BX50015?Clone# ?BP6020?Predicted?Molecular Wt:138kDaPurity: ??ProA?affinity?purified?IgGSpecies Cross-reactivity:HumanForm: ??LiquidApplications:IHC-PSwissprot?ID: ??P04626Background:HER-2?(also?called?HER-2/neu, c-erbB2,?ERBB2 or?neu)?is?a?transmembrane?receptor?tyrosine?kinase,?which?is?a?proto-???oncogene,?i.e.?its activation causes?malignant transformation and?increases the?malignant?potential?(cell?proliferation,invasiveness etc.) of the cells.?In?human cancers?HER-2?is?activated?via?gene?amplification,?which?is?a?genomic?mutation?where?a?small?fragment?at?chromosome?band?17q12-q21?is?multiplied?in?a?cell?up?to?50-100?folds.?HER-2?is?over-expressed?in?15-25% of?primary?breast?cancers, can?also?be?found?in?intestinal?type?gastric?and?gastroesophageal carcinomas, ovarian carcinomas,?high grade endometrial?carcinomas?and?some salivary?duct?tumors.?Low-level?copy?number?????increases?have?been found also?in?rare cases of?lung tumors.?Studies?have shown that c-erbB-2?positive?breast cancer?usually correlates?with?negative?staining?for?estrogen?and?progesterone?receptors; thus a?poorer?predictive outcome?is correlated with?positive?c-erbB-2?staining.?Subcellular?location:MembraneRecommended?method:Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.Immunogen:Synthetic?peptide?according?to?the?aa1155-1255?(C-?terminal) of ?HER-2?was?used?as?an?immunogen.Storage?Buffer:PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.Storage conditions:-25°C?to?-18°CStorage instructions:Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.Recommended?Dilutions:IHC-P:?????1:100-1:200Immunohistochemistry(Formalin/PFA-fixedparaffin-embeddedsections)?analysis ofhuman?breast cancertissue?labelling?HER-2 with?BP6020.?Heat?mediatedantigen?retrieval was?performed?usingTris/EDTA?buffer?pH?9.0Background?References:1.?Olayioye?M.A., et.al. Chem.?274:17209-17218(1999).2.?Wang?S.C., et.al. Cancer?Cell?6:251-261(2004). HKZ150138_BP6020_HER2下載 暫無 說明文檔下載說明書.pdf 上一篇: S100P兔單克隆抗體下一篇: Cytokeratin 5兔單克隆抗體 推薦 CD2兔單克隆抗體 2024年5月22日 1076 暫無 查看全文 O lig2兔單克隆抗體 2024年5月22日 1005 暫無 查看全文 CD23鼠單克隆抗體 2023年7月14日 650 Tested Applications: IF, IHC, WB,ELISA Species Specificity: human, mouse Cited Species: human Positive... 查看全文 GAPDH Antibody(兔抗) 2023年7月14日 1546 暫無 查看全文 您好!請(qǐng)登錄 點(diǎn)擊取消回復(fù) 請(qǐng)登錄后評(píng)論 點(diǎn)擊這里取消回復(fù)。
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