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PAX-5兔單克隆抗體

PAX-5兔單克隆抗體

  • 價格￥1000
  • 規(guī)格100ul
  • 貨號HKZ150259
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150259PAX-5兔單克隆抗體100ul支1000
PAX-5
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50136?Clone# ?BP6140
Predicted?Molecular Wt:
42kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID:??Q02548
Background:
Pax genes area family of developmental?control genes?that?encode?nuclear?transcription?factors?and?have?been?implicated?in?the control of?mammalian?development.
PAX-5?is a?marker for?B-cells,?including?B-lymphoblastic?neoplasms and?maturation stage.?It?is found?in?most?cases?of?mature???and?precursor?B-cell?non-Hodgkin?lymphomas/leukemias.?In approximately 97% of cases?of classic?Hodgkin?lymphoma,?Reed-?Sternberg cells express?PAX-5.
The antibody?is a?useful tool for the?identification of?pro,?pre,?and?mature?B?cells?and?for?classification?of?lymphomas?and?subclassification of classic?Hodgkin’s?lymphoma and anaplastic?large?cell?lymphoma?of the T?and?null-cell?type.
Subcellular?location:
Nucleus
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to?residues within
aa300 to?aa400 of?PAX-5 was?used?as?an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Abdelrasoul?H??etal. Sci?Rep?8:1327?(2018).
2. ?Hijano?DR??etal. Sci?Rep?8:11034?(2018)
Immunohistochemistry
(Formalin/PFA-fixed
paraffin-embedded
sections)?analysis of tonsil?labelling?PAX-5?with
BP6140.?Heat?mediated antigen?retrieval?was
performed?using
Tris/EDTA?buffer?pH?9.0.

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