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GCDFP-15兔單克隆抗體

GCDFP-15兔單克隆抗體

  • 價(jià)格￥600
  • 規(guī)格100ul
  • 貨號(hào)HKZ150237
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150237GCDFP-15兔單克隆抗體100ul支600
GCDFP-15
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50114?Clone# ?BP6118
Predicted?Molecular Wt:
17kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P12273
Background:
GCDFP?isa?prolactin-induced, secretory, actin-binding cytoplasmic?protein, also?designated glycoprotein?(gp).?The?cells?within?the?body that?produce GCDFP-15 appear to?be?restricted?primarily to those with?an?apocrine?function.
It?has?been?reported that cytosolic analysis of?normal tissue from?all?major?organs?has?demonstrated?GCDFP15?in?apocrine
epithelia,?lacrimal, ceruminous and?Moll’s glands and?in?numerous serous?cells?of the?submandibular,?tracheal,?bronchial,
sublingual and?minor salivary glands. Cytosol from?breast?carcinoma?lesions?are?reported?to?contain?GCDFP15?at?a?wide?range?of concentrations. The concentration?is?reported to?be?highest?in?more differentiated carcinomas?and?GCDFP15?shows?only?a??few?positive?individual epithelial cells within?lobules and?small?ducts?in?normal?breast.?Expression?has?also?been?reported?in
fibroadenomas within areas of apocrine?metaplasia.
Subcellular?location:
Cytoplasmic
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to?residues within?aa1-100 of??GCDFP-15 was?used?as?an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Sapino?A,?Cassoni?P?and?Bussolati?G.?Regul.?Homeost.?Agents.?2000;?14(4):259–262.
2. ?Haagensen?DE?Jr,?Dilley?WG,?Mazoujian?G?et?al.?Ann.?NY Acad. Sci.?1990;586:161–173.
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections)?analysis of
breast?carcinoma tissue?labelling?GCDFP-15?with BP6118.?Heat?mediated antigen?retrieval was
performed?using
Tris/EDTA?buffer?pH?9.0

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