一抗 抗體 試劑 Estrogen Receptor – α兔單克隆抗體一抗 抗體 試劑 價(jià)格¥1400規(guī)格100ul貨號(hào)HKZ150144單位支品牌HaoKebio QQ53383090 咨詢購買 產(chǎn)品介紹產(chǎn)品參數(shù)資料下載 品牌商品編碼商品名稱規(guī)格單位單價(jià)HaoKebioHKZ150144Estrogen Receptor – α兔單克隆抗體100ul支1400Estrogen?Receptor?(ER)?αRecombinant?Rabbit?Monoclonal Antibody?Product?Datasheet?Catalog# ?BX50021?Clone# ?BP6026?Predicted?Molecular Wt:66kDaPurity: ??ProA?affinity?purified?IgGSpecies Cross-reactivity:HumanForm: ??LiquidApplications:IHC-PSwissprot?ID: ??P03372?Background:Estrogen?receptor?(ER)?belongs to the?steroid?receptor superfamily of?nuclear?receptors.?It?is?a?protein with?553?amino?acids.?The?receptor?molecule?has three domains,?i.e. the central?DNA-binding domain, the?hormone-binding?domain?at?the?C-terminal, and the transcription-activating domain at the?N-terminal.?ER?mediates?regulatory?functions?of female?sex?steroids,???mainly?17?(E2), on growth, differentiation and function?in?several?target?tissues,?including?female?and?male?reproductive?tract,?mammary gland, and skeletal and?cardiovascular?systems.?Studies?have shown?ER α?is?present?in the?nuclei of epithelial?cells?in?normal?breast?and?endometrial?tissues,?as?well?as?a?subset?of?breast carcinomas.Studies with?immunohistochemical assay show that?positive steroid?hormone status?has?predicted?favourable?overall,?survival,?independently of?hormonal treatment. Secondly,?ER α can?be?used?as?a?tumour?marker,?preferentially?in?combination?with?an???antibody to?progesterone?receptor,e.g.,?in the classification of adenocarcinomas.?Subcellular?location:NuclearRecommended?method:Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.Immunogen:Synthetic?peptide corresponding to?ER alpha?residueswithin?aa495‐595 of?ER?alpha?was?used?as?an immunogen.Storage?Buffer:PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.Storage conditions:-25°C?to?-18°CStorage instructions:Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.Recommended?Dilutions:IHC-P:?????1:100-1:200Background?References:1.?Stein?B, et.al,?Mol?Cell?Biol.?1995 Sep;15(9):4971-9.2.?Saville?B, et.al,J?Biol?Chem.?2000?Feb?25;275(8):5379-?87.Immunohistochemistry?(Formalin/PFA-fixedparaffin-embeddedsections)?analysis ofhuman?breast cancertissue?labelling?ER?α with BP6026.?Heat?mediated ??antigen?retrieval?wasperformed?usingTris/EDTA?buffer?pH?9.0 HKZ150144_BP6026_ERα下載 暫無 說明文檔下載說明書.pdf 上一篇: SOX10兔單克隆抗體下一篇: CD3兔單克隆抗體 推薦 熒光五標(biāo)信號(hào)放大試劑盒(石蠟切片適用) 2024年12月10日 1835 查看全文 CD163 兔單克隆抗體 2024年12月2日 1166 存儲(chǔ)說明: 以藍(lán)冰運(yùn)輸。收貨后,進(jìn)行分裝,并在-25°C 至-18°C 條件下儲(chǔ) 存。避免反復(fù)凍融。 推薦稀釋比: IHC-P: 1:... 查看全文 組織自發(fā)熒光淬滅劑 2024年9月14日 1460 暫無 查看全文 CA125兔單克隆抗體 2024年5月20日 978 暫無 查看全文 您好!請(qǐng)登錄 點(diǎn)擊取消回復(fù) 請(qǐng)登錄后評(píng)論 點(diǎn)擊這里取消回復(fù)。
CD163 兔單克隆抗體 2024年12月2日 1166 存儲(chǔ)說明: 以藍(lán)冰運(yùn)輸。收貨后,進(jìn)行分裝,并在-25°C 至-18°C 條件下儲(chǔ) 存。避免反復(fù)凍融。 推薦稀釋比: IHC-P: 1:... 查看全文
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