ARL13B兔多克隆抗體

價(jià)格￥2800
規(guī)格200ul
貨號(hào)HK210015L
單位支
品牌HaoKebio

產(chǎn)品介紹

產(chǎn)品參數(shù)

資料下載

品牌	商品編碼	商品名稱	規(guī)格	單位	單價(jià)
HaoKebio	HK210015L	ARL13B兔多克隆抗體	200ul	支	2800

Applications

Tested Applications:
IF, IHC, IP, WB,ELISA

Cited Applications:
IF, IHC, IP, WB
Species Specificity:
human, mouse, rat, Canine

Cited Species:
canine, chicken, human, mouse, pig, rat, sheep, Xenopus, zebrafish

Positive WB detected in:
mouse liver tissue, NIH/3T3 cells, L02 cells, mouse kidney tissue, rat liver tissue, mouse brain tissue

Positive IP detected in:
L02 cells

Positive IHC detected in:
mouse brain tissue, human testis tissue, human liver tissue, human kidney tissue
Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0

Positive IF detected in:
MDCK cells, hTERT-RPE1, mouse embryonic fibroblasts, NIH3T3 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:500
IF : 1:50-1:500
Product Information

Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20^oC storage.
Immunogen Information

Full name:
ADP-ribosylation factor-like 13B

Calculated molecular weight:
48 kDa

Observed molecular weight:
40-48 kDa, 66 kDa

Gene symbol
ARL13B

Synonyms
ARL13B, ARL2 like protein 1, ARL2L1, JBTS8
Background
ARL13B, also named as ARL2L1, is a small ciliary G protein of the Ras superfamily. Localized in the cilia, it is required for cilium biogenesis and sonic hedgehog signaling. Defects in ARL13B are the cause of Joubert syndrome (JS) which is an autosomal recessive disorder characterized by a distinctive cerebellar malformation (PMID: 19906870).This antibody detects two speci?c bands at 60 kDa and 48 kDa. Arl13b is predicted to be a 48 kDa protein, and the 60 kDa band is likely to represent a modified form of Arl13b. ARL13B can be used to mark the cilia (PMID:22072986).

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