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Brachyury兔單克隆抗體

Brachyury兔單克隆抗體

  • 價(jià)格￥1800
  • 規(guī)格100ul
  • 貨號(hào)HKZ150364
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150364Brachyury兔單克隆抗體100ul支1800
Brachyury
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50241?Clone# ?BP6218
Predicted?Molecular Wt:
47kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID:??O15178
Background:
Brachyury?protein, encoded?by the T gene,?is a transcription factor?that?is?vital?for?the?formation?of?posterior?mesoderm?and????axial development during vertebrate embryogenesis.?Human?brachyury?is expressed?in?the?notochord,?as?well?as?in?chordoma?tumors that occur along the spine,?making?it?a good?marker?for?notochord?and?notochord-derived?tumors.?A?common
polymorphism?in the?human T gene?has also?been shown to?be?associated?with?development?of the?multifactorial?neural?tube?defect, spina?bifida.
Subcellular?location:
Nuclear
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Recombinant fragment within?Human?Brachyury.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA
0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store
at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Vujovic, S. et?al.?(2006) J?Pathol?209,?157-65.
2.?Yang, X.R. et?al.?(2009)?Nat?Genet?41,?1176-8.
Immunohistochemistry
(Formalin/PFA-fixed?paraffin-?????embedded?sections)?analysis of
human?chordoma tissue
labelling?Brachyury?with?BP6218.?Heat?mediated?antigen?retrieval???was?performed?using Tris/EDTA????buffer?pH?9.0

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