SOX2兔單克隆抗體

價格￥1000
規(guī)格100ul
貨號HKZ150242
單位支
品牌HaoKebio

產(chǎn)品介紹

產(chǎn)品參數(shù)

資料下載

品牌	商品編碼	商品名稱	規(guī)格	單位	單價
HaoKebio	HKZ150242	SOX2兔單克隆抗體	100ul	支	1000

SOX2
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50119?Clone# ?BP6123
Predicted?Molecular Wt:
34kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P48431
Background:
The SOX2 gene encodes a?member of the?SRY-related?HMG-box?(SOX)?family?of transcription?factors.?SOX2?is?expressed?in
multipotent?neuronal stem cells, and?may aid to?identify?cells that?are?capable?of?self-renewal?and?multipotent?differentiation.?SOX2?has?been shown to?be a?negative?prognostic factor?and?associated?with?aggressive?phenotypes?in?breast,?head?and?neck,?gastric, colorectal and?bladder cancers.?In small?cell?lung?cancers,?SOX2?was?also?correlated?with?a?poor?prognosis.?Conversely,??SOX2?is expressed?in a?high?percentage of?lungsquamous cell carcinomas?and?was?shown?to?bean?independent?positive
prognostic?marker.Subcellular?location:
Nucleus
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to?residues within
aa1-100 of??Human?SOX2 was?used?as?an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Yang?F,?et?al.?Int?J?Clin?Exp?Pathol.?2013?Nov?15;?6
(12):2846-54.
2.?Wilbertz?T, et?al.?Mod?Pathol.?2011 Jul;?24?(7):944-53.
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections)?analysis of?Lung?squamous?cell
carcinomas tissue
labelling SOX2?with
BP6123.?Heat?mediated antigen?retrieval was
performed?using
Tris/EDTA?buffer?pH?9.0

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