RRM1兔單克隆抗體

價(jià)格￥2200
規(guī)格100ul
貨號(hào)HKZ150241
單位支
品牌HaoKebio

產(chǎn)品介紹

產(chǎn)品參數(shù)

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品牌	商品編碼	商品名稱	規(guī)格	單位	單價(jià)
HaoKebio	HKZ150241	RRM1兔單克隆抗體	100ul	支	2200

RRM1
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50118?Clone# ?BP6122
Predicted?Molecular Wt:
90kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P23921
Background:
Ribonucleotide?reductase?M1?polypeptide?(RRM1)?is one of two?non-identical subunits for?ribonucleoside-diphosphate
reductase, an enzyme which catalyzes the?biosynthesis?of?deoxyribonucleotides from the?corresponding?ribonucleotides.?It
provides the?precursors?necessary for?DNA synthesis.?RRM1?is?present throughout the cell?division?cycle?but?downregulated?in??quiescent cells.?RRM1?is?involved?in carcinogenesis, tumor?progression, and the?response?of?non-small-cell?lung?cancer?(NSCLC)?to chemotherapy.
Subcellular?location:
Cytoplasmic
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to?residues within?aa700-800 of??Human?RRM1 was?used?as?an
immunogen.
Storage?Buffer:
0.05%. ??????????????????????????????????????????????????????????????????????????????????????
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Wang,Q, et?al.?PLoS?ONE.?2013 Jul;8(7):1-12.
2. ??Nordlund?P, et?al. Annu?Rev?Biochem.?2006; 75:681–706.
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections)?analysis of
breast?carcinoma tissue?labelling?RRM1 with
BP6122.?Heat?mediated antigen?retrieval was
performed?using
Tris/EDTA?buffer?pH?9.0

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