一抗 抗體 試劑 Ep-CAM兔單克隆抗體一抗 抗體 試劑 價格¥600規(guī)格100ul貨號HKZ150174單位支品牌HaoKebio QQ53383090 咨詢購買 產(chǎn)品介紹產(chǎn)品參數(shù)資料下載 品牌商品編碼商品名稱規(guī)格單位單價HaoKebioHKZ150174Ep-CAM兔單克隆抗體100ul支600EpCAMRecombinant?Rabbit?Monoclonal Antibody?Product?DatasheetCatalog# ?BX50051?Clone# ?BP6056Predicted?Molecular Wt:35kDaPurity: ??ProA?affinity?purified?IgGSpecies Cross-reactivity:HumanForm: ??LiquidApplications:IHC-PSwissprot?ID: ??P16422Background:Epithelial cell adhesion?molecule?(EpCAM)?is a transmembrane glycoprotein,?may?act?as?a?physical?homophilic?interaction?molecule?between?intestinal epithelial cells?(IECs) and?intraepithelial?lymphocytes?(IELs) at?the?mucosal?epithelium forproviding?immunological?barrier as a first?line of defense?against?mucosal?infection.?It?plays?a?role?in?embryonic?stem?cells?proliferation and differentiation, and?it?up-regulates the expression?ofFABP5,?MYC?and?cyclins?A?and?E.This glycoprotein?is?located on the cell?membrane surface?(preferentially?basolaterally)?and?in the?cytoplasm?of virtually?allepithelial cells with the exception of?most?squamous?epithelia,?hepatocytes,?renal?proximal tubular?cells,?gastric?parietal?cells?and?myoepithelial cells.?However, focal?positivity?may?be?seen?in the?basal?layer of?squamous?cell?epithelium?of?endoderm(e.g.,?palatine?tonsils) and?mesoderm?(e.g.,?uterine?cervix).?Normal?mesothelial?cells?are?EpCAM?negative,?but?may?express focal?reaction when?undergoing?reactive changes.?EpCAM?has?been seen?in the?majority of?epithelial?neoplasms,?whereas??most?non-epithelial?neoplasms do?not show?EpCAM expression.In conjunction with other?markers,?EpCAM can?be?used?as?an?aid?in?determining?neoplasms?of?epithelial?origin,?such?as?distinguishing?between?lung adenocarcinoma and?mesothelioma.Subcellular?location:MembraneRecommended?method:Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.Immunogen:Synthetic?peptide corresponding to?EpCAM?residues?????within?aa1-100 of?EpCAM?was?used?as?an?immunogen.Storage?Buffer:PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.Storage conditions:-25°C?to?-18°CStorage instructions:Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.Recommended?Dilutions:IHC-P:?????1:100-1:200Background?References:1. ?Latza?et?al. J?Clin?Pathol.?1990;43:213-19.2.?Ordonez?NG?et?al. Am?J?Clin?Pathol?1998;109(1):85-89.Immunohistochemistry?(Formalin/PFA-fixedparaffin-embeddedsections?analysis of?colon?tissue?labelling?EpCAMwith?BP6056.?Heat mediated?antigenretrieval?was?performed?using Tris/EDTA?buffer????pH?9.0 HKZ150174_BP6056_EpCAM_下載 暫無 說明文檔下載說明書.pdf 上一篇: CD1a兔單克隆抗體下一篇: Type II Cytokeratins兔單克隆抗體 推薦 樣本杯(含多聚甲醛) 2023年7月4日 1282 暫無 查看全文 F4/80 兔單克隆即用型抗體 2024年12月2日 1132 存儲說明: 以藍冰運輸。收貨后,進行分裝,并在-25°C 至-18°C 條件下儲 存。避免反復凍融。 背景參考文獻: 1.?Hirsch, S. et a... 查看全文 組蛋白抽提試劑盒 2024年9月18日 1126 服務介紹: 無 暫無 查看全文 ERp19兔多克隆抗體 2024年10月12日 1135 暫無 查看全文 您好!請登錄 點擊取消回復 請登錄后評論 點擊這里取消回復。
F4/80 兔單克隆即用型抗體 2024年12月2日 1132 存儲說明: 以藍冰運輸。收貨后,進行分裝,并在-25°C 至-18°C 條件下儲 存。避免反復凍融。 背景參考文獻: 1.?Hirsch, S. et a... 查看全文
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