一抗 抗體 試劑 GATA-3兔單克隆抗體一抗 抗體 試劑 價(jià)格¥1000規(guī)格100ul貨號(hào)HKZ150375單位支品牌HaoKebio QQ53383090 咨詢購(gòu)買 產(chǎn)品介紹產(chǎn)品參數(shù)資料下載 品牌商品編碼商品名稱規(guī)格單位單價(jià)HaoKebioHKZ150375GATA-3兔單克隆抗體100ul支1000GATA-3Recombinant?Rabbit?Monoclonal Antibody?Product?DatasheetCatalog# ?BX50252?Clone# ?BP6229Predicted?Molecular Wt:48kDaPurity: ??ProA?affinity?purified?IgGSpecies Cross-reactivity:HumanForm: ??LiquidApplications:IHC-PSwissprot?ID: ??P23771Background:GATA?binding?protein?3 or GATA-3,?is a zinc finger?transcription?factor?and?plays?an?important?role?in?promoting?and?directing?cell?proliferation, development, and differentiation?in?many tissues?and?cell?types.GATA-3?is?one?of?the?three?genes?mutated?in?10% of?breast?cancers.?Nuclear?expression?of?GATA-3?in?breast?cancer?isconsidered a?marker of?luminal cancer?in?ER+ cancer?and?luminalandrogen?responsive?cancer?in?ER-/AR+ tumors.?It?is?highly?coexpressed with?FOXA1 and serves as?negative?predictor?of?basal?subtype?and?HER-2?and?is?also?considered?a?strongpredictor of taxane and?platin salts?insensitivity.GATA-3 expression?is found?in?urothelial carcinoma, especially?in?invasive and?high?grade?tumors.?Therefore,?GATA-3?can?beused?in a?panel of antibodies for diagnosis?of?unknown?primary?carcinoma,?when?carcinomas?of the?breast?or?bladder?areapossibility. Studies?have also shown the?utility of?GATA-3?in?differntiatingurothelial?carcinoma?from?prostate?adenocarcinoma?and squamous cell carcinomas of the?uterine,?cervix,?anus?and?lung.Subcellular?location:NucleusRecommended?Method:Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.Immunogen:Synthetic?peptide. This?information?is?proprietary to?Biolynx.Storage?Buffer:PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.Storage Conditions:-25°C?to?-18°CShipment?Instructions:Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?-18?°C. Avoid?freeze?/ thaw?cycles.Recommended?Dilution:IHC-P:?????1:100-1:200Background?References:1.?Voduc?D, et?al.?Cancer?Epidemiol?Biomarkers?Prev.2008?Feb;17(2):365-73.2. ?Miettinen?M, et?al. Am?J?Surg?Pathol.?2014 Jan;?38(1):?13–22.Immunohistochemistry?(Formalin/PFA-fixed?paraffin-embedded?sections)?analysis of ?invasive?ductal carcinoma?of?the?breast?labelling?GATA-3 with?BP6229. HKZ150375_BP6229_GATA-3下載 暫無 說明文檔下載說明書.pdf 上一篇: Glypican -3兔單克隆抗體下一篇: CDK4兔單克隆抗體 推薦 5%BSA溶液,無菌 2024年11月11日 1656 暫無 查看全文 smooth muscle actin 兔單克隆即用型抗體 2024年12月2日 1202 存儲(chǔ)說明: 以藍(lán)冰運(yùn)輸。收貨后,進(jìn)行分裝,并在-25°C 至-18°C 條件下儲(chǔ) 存。避免反復(fù)凍融。 背景參考文獻(xiàn): 1.?TSLP/TSLPR prom... 查看全文 E-Cadherin 兔單克隆抗體 2024年12月4日 1421 背景: 鈣粘蛋白是一個(gè)跨膜糖蛋白家族,介導(dǎo)鈣依賴性細(xì)胞間粘附,在維持正常組織結(jié)構(gòu)中發(fā)揮重要作用。 e-鈣粘蛋白(上皮鈣粘蛋白),... 查看全文 Villin兔單克隆抗體 2024年5月21日 892 暫無 查看全文 您好!請(qǐng)登錄 點(diǎn)擊取消回復(fù) 請(qǐng)登錄后評(píng)論 點(diǎn)擊這里取消回復(fù)。
smooth muscle actin 兔單克隆即用型抗體 2024年12月2日 1202 存儲(chǔ)說明: 以藍(lán)冰運(yùn)輸。收貨后,進(jìn)行分裝,并在-25°C 至-18°C 條件下儲(chǔ) 存。避免反復(fù)凍融。 背景參考文獻(xiàn): 1.?TSLP/TSLPR prom... 查看全文
E-Cadherin 兔單克隆抗體 2024年12月4日 1421 背景: 鈣粘蛋白是一個(gè)跨膜糖蛋白家族,介導(dǎo)鈣依賴性細(xì)胞間粘附,在維持正常組織結(jié)構(gòu)中發(fā)揮重要作用。 e-鈣粘蛋白(上皮鈣粘蛋白),... 查看全文
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