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Ch romogranin A兔單克隆抗體

Ch romogranin A兔單克隆抗體

  • 價(jià)格￥600
  • 規(guī)格100ul
  • 貨號HKZ150248
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150248Ch romogranin A兔單克隆抗體100ul支600
Chromogranin A
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50125?Clone# ?BP6129
Predicted?Molecular Wt:
51kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P10645
Background:
Chromogranin A?(CGA)?is an acidic?protein which?is?reported to?be widely?expressed?in?neural?tissues?and?in?secretory?granules?of?human?endocrine cells eg?parathyroid gland, adrenal?medulla,?anterior?pituitary gland,?islet?cells?of the?pancreas?and?C?cells?of the thyroid.
CGA?is found?in the?large?majority of epithelial?NE tumours:?pituitary adenomas,?parathyroid?and?pancreatic?islet?cell?tumours,?medullary thyroid carcinoma, and carcinoid?tumours.
Together with synaptophysin, CGA?is the?most?important?marker for the?identification?of?NE?and?neuronal tumours?and?NE/neuronal differentiation?in other tumours.
Subcellular?location:
Cytoplasm
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to?residues within?aa400 to?aa600 of?Chromogranin?A?was?used?as?an ?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1. ?Konecki?DS,?Benedum?UM, Gerdes?HH?etal. J?Biol?Chem 1987;262:17026-17030.
2. ?Lloyd?RV,?Cano?M,?Rosa?P,?et?al. Am?J?Pathol 1988;130:296-304.
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded??sections)?analysis of?colon?labelling
Chromogranin A with
BP6129.?Heat?mediated antigen?retrieval was
performed?using
Tris/EDTA?buffer?pH?9.0.

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