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CD38兔單克隆抗體

CD38兔單克隆抗體

  • 價(jià)格¥600
  • 規(guī)格100ul
  • 貨號(hào)HKZ150200
  • 單位
  • 品牌HaoKebio

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HaoKebioHKZ150200CD38兔單克隆抗體100ul600
CD38
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50077?Clone# ?BP6082
Predicted?Molecular Wt:
34kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P28907
Background:
CD38, also?known as ADP-ribosyl cyclase, synthesizes the?second?messagers?cyclic?ADP-ribose?and?nicotinate-adenine
dinucleotide?phosphate, the former a second?messenger for glucose-induced?insulin?secretion.?CD38?also?has?cADPr?hydrolase?activity.?It?is found on?immature cells of the?B?and T?cell?lineages?but?not?on?most?mature?resting?peripheral?lymphocytes.?It?is
also?present on thymocytes,?pre-B cells, germinal center?B?cells,?mitogen-activated?T?cells,?Ig-secreting?plasma?cells,?monocytes,?NK cells, erythroid and?myeloid?progenitors?in the?bone?marrow?and?brain?cells.
CD38?isuesd to?identify?plasma cells and?plasmablastic differentiation, and?evaluate?the?prognosis?for?B-cell?chronic?lymphocytic?leukemia?(CLL)?patients.
Subcellular?location:
Membrane
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to?residues within?aa200-300 of?CD38 was?used?as?an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Chini?CC??et?al.?Clin?Cancer?Res?20:120-30?(2014).
2.??Kobayashi?M??etal. World?J?Gastroenterol?20:3597-608?(2014).
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections)?analysis of
tonsil?labelling?CD38 with BP6082.?Heat?mediated ???antigen?retrieval?was
performed?using
Tris/EDTA?buffer?pH?9.0.

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