CD3兔單克隆抗體

價格￥600
規(guī)格100ul
貨號HKZ150157
單位支
品牌HaoKebio

產(chǎn)品介紹

產(chǎn)品參數(shù)

資料下載

品牌	商品編碼	商品名稱	規(guī)格	單位	單價
HaoKebio	HKZ150157	CD3兔單克隆抗體	100ul	支	600

CD3
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
?
Catalog# BX50034?Clone# ?BP6039
?
Predicted?Molecular Wt:
23kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P07766
Background:
Cluster?of?differentiation?3?(CD3)?is?a?multimeric
protein complex,?known?historically as the T3 complex,?and?is composed of four distinct?polypeptide?chains;
epsilon?(ε), gamma?(γ), delta?(δ) and?zeta?(ζ),?that
assemble?and?function?as?three?pairs?of?dimers?(εγ,?εδ,??ζζ). The?CD3 complex?serves?as?a?T?cell?co-receptor?that associates?noncovalently with the T cell?receptor?(TCR).
?
CD3 antigen appearance at?all?stagesofT?cell
development, and?makes?it anideal T cell?marker?for?both the detection of?normal T?cells?and?T?cell
neoplasms?(lymphomas and?leukemias).
Subcellular?location:
Membrane
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to CD3E?residues
within?aa100-200 of?CD3E?was?used?as?an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Smith-Garvin?JE, et.al, Annu?Rev?Immunol.?2009;27:591-619.
2.?SalvadoriS, et.al, J?Immunol.?1994?Dec?1;153(11):5176-?82.
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections analysis?of tonsil?tissue?labelling?CD3 with??BP6039.?Heat?mediated ???antigen?retrieval was
performed?using
Tris/EDTA?buffer?pH?9.0

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