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COX-2兔單克隆抗體

COX-2兔單克隆抗體

  • 價(jià)格¥5512.5
  • 規(guī)格1ml
  • 貨號(hào)HKI0591B
  • 單位
  • 品牌HaoKebio

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HaoKebioHKI0591BCOX-2兔單克隆抗體1ml5512.5

Applications

Tested Applications:

IF, IHC, WB, ELISA


Cited Applications:

IF, IHC, WB


Species Specificity:

human, mouse


Cited Species:

human, mouse, rat


Positive WB detected in:

A549 cells, mouse lung tissue


Positive IHC detected in:

human lung tissue, human spleen tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Positive IF detected in:

mouse lung tissue


Recommended dilution:

WB : 1:500-1:1000

IHC : 1:100-1:400

IF : 1:50-1:500

Product Information


Source:

Rabbit


Purification method:

Antigen affinity purification


Isotype:

IgG


Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)


Calculated molecular weight:

604 aa, 68 kDa


Observed molecular weight:

69 kDa


Gene symbol

PTGS2


Synonyms

COX 2, COX2, COX2/ Cyclooxygenase 2, COX2/ Cyclooxygenase 2/ PTGS2, Cyclooxygenase 2, GRIPGHS, hCox 2, PGG/HS, PGH synthase 2, PGHS 2, PHS 2, PHS II, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, PTGS2

Background

COX2 (Prostaglandin G/H synthase 2, PTGS2) mediates the formation of prostaglandins from arachidonate. Its subunit structure is homodimer. The fully N-glycosylated PTGS2 is 72-74 kDa and the aglycosylated is 66 kDa(PMID:19656660 ). It also expresses a band of 39 kDa after unspecific cleavage(PMID:17509125 ). The 50 kDa band of fragmented PTGS2 has also previously been detected in AD brains(PMID:14724276 ).

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