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Melan A兔單克隆抗體

Melan A兔單克隆抗體

  • 價(jià)格￥1400
  • 規(guī)格100ul
  • 貨號(hào)HKZ150204
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150204Melan A兔單克隆抗體100ul支1400
Melan-A
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50081?Clone# ?BP6086
Predicted?Molecular Wt:
13kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID:??Q16655
Background:
Melan-A?is?involved?in?melanosome?biogenesis?by ensuring the stability of GPR143?and?plays?a?vital?role?in?the?expression,????stability, trafficking, and?processing of?melanocyte?protein?PMEL, which?is critical to?the?formation?of?stage?II?melanosomes.
Melan-A?is specifically expressed?in?malignant?melanoma.
Melan-A?is one of the?most valuable?melanoma?markers.?Melan-A?is?useful?in confirming?melanocytic?differentiation?of?primary cutaneous tumours, differentiating these from?neurothekeoma and?benign?fibrous?histiocytoma.
Subcellular?location:
Cytoplasm
Recommended?Method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Full?length?protein corresponding to?Human?Melan-A.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage Conditions:
-25°C?to?-18°C
Shipment?Instructions:
Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?–?18°C. Avoid?freeze?/ thaw?cycles.
Recommended?Dilution:
IHC-P:?????1:100-1:200
Background?References:
1. ?Hoashi?T., Watabe?H.,?Muller?J.,Vieira?W.D.,?Hearing V.J.J.?Biol. Chem.?280:14006-14016(2005)
2.?Giordano?F.,?Bonetti?C., Surace?E.M.,?Marigo?V.,?Raposo G.Hum.?Mol. Genet.?18:4530-4545(2009)
Immunohistochemistry?(Formalin/PFA-fixed?paraffin-?embedded?sections)?analysis of?malignant?melanoma?labelling?Melan-A?with?BP6086.

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