Thyroglobulin兔單克隆抗體

價(jià)格￥600
規(guī)格100ul
貨號(hào)HKZ150185
單位支
品牌HaoKebio

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產(chǎn)品參數(shù)

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品牌	商品編碼	商品名稱	規(guī)格	單位	單價(jià)
HaoKebio	HKZ150185	Thyroglobulin兔單克隆抗體	100ul	支	600

Thyroglobulin
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50062?Clone# ?BP6067
Predicted?Molecular Wt:
305kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P01266
Background:
Thyroglobulin?(TG)?is a dimeric glycoprotein specific to the?thyroid?gland?which?belongs?to?the?type-B?carboxylesterase/lipase?family.?It?is the?precursor of the?iodinated thyroid?hormones triiodothyronine?(T3) and thyroxine?(T4). Variations?in TG?are
associated with susceptibility to autoimmune thyroid?disease type?3.?Defective?or?impaired TG?synthesis?usually?results?in
congenital goitrous?hypothyroidism, virtual absence of TG?in thyroid tissue,?and the?presence?of?an?elevated?concentration?of?iodoalbumin. The final?result of these abnormalities?is a?decreased?rate of T3?and?T4?synthesis.
Thyroglobulin?is found?in?normal thyroid and differentiated thyroid carcinoma?cells,?but?not?undifferentiated?thyroid.?It?is?a?useful?marker for?identification of tumors with thyroid origin.
?Subcellular?location:
Cytoplasm
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding?to Thyroglobulin
residues?within?aa350-450 of??Thyroglobulin?was?used as an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Abrosimov?A?et?al. Arkh?Patol.?1996 Jul;58(4):43-8.
2. ?Pastolero?GC?et?al. Am?J?Surg?Pathol.?1996?Feb;20(2):245-50.
Immunohistochemistry?(Formalin/PFA-fixedparaffin-embedded
sections analysis?of
thyroid cancer tissue
labelling thyroglobulin?with?BP6067.?Heat
mediated?antigen
retrieval?was?performed?using Tris/EDTA?buffer????pH?9.0

HKZ150185_BP6067_ Thyroglobulin 下載

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