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CEA兔單克隆抗體

CEA兔單克隆抗體

  • 價(jià)格￥600
  • 規(guī)格100ul
  • 貨號(hào)HKZ150203
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150203CEA兔單克隆抗體100ul支600
CEA
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50080?Clone# ?BP6085
Predicted?Molecular Wt:
77kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P06731
Background:
Carcinoembryonic antigen?(CEA)?is a glycoprotein?produced?in colorectal?cancer tissues.?In?normal?adult?tissue,?CEA?is
expressed?in the apical?border and, to a?lesser?extent?in the?cytoplasm,?of?the?columnar?cells?of?colon,?small?intestine,?stomach?(surface epithelium,?mucous?neck cells and weakly?in?pyloric?mucous cells),?pancreatic?ducts,?secretory?epithelia?of?sweat
glands, squamous epithelial cells of the tongue,?esophagus,uterine?cervix,?and?urothelium.
The CEA antibody?is a?useful aid for?classification?of?adenocarcinomas,?notably?in?the?gastrointestinal?tract,?including?colonic????and?pancreatic carcinomas.?IHC?results also aid?in the classification?of?secretory?meningiomas?and?medullary?carcinoma?of the?thyroid.Subcellular?location:
Cytoplasmic and?lumenal?membrane
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Natural?protein within?full?length?CEA was?used as?an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1. ??Probst-CousinS, Villagran-Lillo?R,?Lahl?R,?Bergmann?M,?Schmid?KW, Gullotta?F. Cancer?1997,79:2003-15.
2. ?Nollau?P, et?al.?Cancer?Res.?1997 Jun; 57(12):2354-57.
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections)?analysis of
colon?carcinoma?lab-?????elling?CEA?with?BP6085.??Heat?mediated?antigen???retrieval?was?performed?using Tris/EDTA?buffer????pH?9.0?

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