NapsinA兔單克隆抗體

品牌	商品編碼	商品名稱	規(guī)格	單位	單價
HaoKebio	HKI0661B	NapsinA兔單克隆抗體	1ml	支	10106.25

Applications

Tested Applications:

IF, IHC, WB,ELISA

---

Species Specificity:

human, mouse

---

Positive WB detected in:

mouse lung tissue

---

Positive IHC detected in:

human lung cancer tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

---

Positive IF detected in:

PC-3 cells

---

Recommended dilution:

WB : 1:500-1:1000

IHC : 1:50-1:500

IF : 1:10-1:100

Product Information

---

Source:

Rabbit

---

Purification method:

Antigen affinity purification

---

Isotype:

IgG

---

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Immunogen Information

---

Full name:

napsin A aspartic peptidase

---

Calculated molecular weight:

420 aa, 45 kDa

---

Observed molecular weight:

45-55 kDa

---

Gene symbol

NAPSA

---

Synonyms

Asp 4, ASP4, Aspartyl protease 4, KAP, Kdap, NAP1, NAPA, NAPSA, Napsin 1, Napsin A, napsin A aspartic peptidase, Pronapsin A, SNAPA, TA01/TA02

Background

Napsin is found in two isoforms, napsin A and B, with highly homologous nucleotide sequences (91.2%). Napsin A appears to be a functional proteinase, predominantly expressed in lung and kidney. Napsin B is transcribed exclusively in cells related to the immune system and lacks an in-frame stop codon and is believed to be a pseudogene.(PMID:12698189). Napsin A is superior to TTF-1 in distinguishing primary lung ACA from other carcinomas (except kidney), particularly primary lung small cell carcinoma, and primary thyroid carcinoma.(PMID:22288963).