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INSM-1兔單克隆抗體

INSM-1兔單克隆抗體

  • 價格￥1800
  • 規(guī)格100ul
  • 貨號HKZ150386
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150386INSM-1兔單克隆抗體100ul支1800
INSM-1
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50263?Clone# ?BP6240
Predicted?Molecular Wt:
53kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID:??Q01101
Background:
INSM-1?(insulinoma-associated?protein?1), also?known?as?zinc-finger?protein?IA-1,?is?a?developmentally?regulated?zinc-finger
transcription factor.?It?localizes to the?nucleus and?is expressed?in embryonic tissues?undergoing?neuroendocrine
differentiation.?It?plays an?important?role?in?neuroendocrine development and?is?required for?normal?differentiation?of?pancreatic endocrine cells.?Inhibition of?INSM-1?results?in?decreased formation?of glucagon?and?Insulin?positive?cells.
INSM-1?is?not expressed?in?normal adult tissues?but?it can?be found?highly?expressed?in?neuroendocrine?tumors.?INSM-1?is?mainly?used?in clinical diagnosis of?neuroendocrine tumors.
Subcellular?location:
Nucleus
Recommended?Method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide. This?information?is?proprietary to?Biolynx.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage Conditions:
-25°C?to?-18°C
Shipment?Instructions:
Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?-18?°C. Avoid?freeze?/ thaw?cycles.
Recommended?Dilution:
IHC-P:?????1:100-1:200
Background?References:
1.?Chen,?C.,?et?al.?2019.?Mol. Cancer?Res.?17:?1597-1604.
2.?Song,?R., et?al.?2020.Carcinogenesis?41:?326-333.
Immunohistochemistry?(Formalin/PFA-fixed?paraffin-
embedded?sections)?analysis of ?small?cell?neuroendocrine?carcinoma?labelling?INSM-1 with?BP6240.

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