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AR-V7兔單克隆抗體

AR-V7兔單克隆抗體

  • 價(jià)格￥1000
  • 規(guī)格100ul
  • 貨號(hào)HKZ150297
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150297AR-V7兔單克隆抗體100ul支1000
AR?V7
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50174?Clone# ?BP6152
Predicted?Molecular Wt:
80kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID:??C0JKD3
Background:
AR V7?belongs to the?nuclear?hormone?receptor family.?It Contains?nuclear?receptor?DNA-binding domain.?Steroid?hormone
receptors are?ligand-activated transcription factors that?regulate eukaryotic gene?expression?and?affect?cellular?proliferation????and differentiation?in target tissues. Transcription factor activity?is?modulated?by?bound?coactivator?and?corepressor?proteins.?This?target?is?a?splice?variant?of?Androgen?receptor?(UniProt?P10275)?lacking?the?C-terminal?androgen?binding?site.
Subcellular?location:
Nucleus
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide?(the amino acid sequence?is
considered to?be commercially sensitive) within?Human?Androgen?Receptor(AR-V7 specific) aa?600 to?the?C-
terminus.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Chen?W??etal. J?Cell?Biochem?120:14055-14064?(2019).
2.??Honda?M??etal.?Prostate?79:1043-1052?(2019).
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded sections)?analysis of?prostate
adenocarcinoma tissue
labelling AR V7??with
BP6152.?Heat?mediated
antigen?retrieval?was
performed?using Tris/EDTA?buffer?pH?9.0

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