一抗 抗體 試劑 Cytokeratin 8&18兔單克隆抗體Cocktail一抗 抗體 試劑 價(jià)格¥600規(guī)格100ul貨號(hào)HKZ150268單位支品牌HaoKebio QQ53383090 咨詢購買 產(chǎn)品介紹產(chǎn)品參數(shù)資料下載 品牌商品編碼商品名稱規(guī)格單位單價(jià)HaoKebioHKZ150268Cytokeratin 8&18兔單克隆抗體Cocktail100ul支600Cytokeratin?8&18Recombinant?Rabbit?Monoclonal Antibody?Product?DatasheetCatalog# ?BX50145 Clone#??BP6005&BP6054Predicted?Molecular Wt:54/48kDaPurity: ??ProA?affinity?purified?IgGSpecies Cross-reactivity:HumanForm: ??LiquidApplications:IHC-PSwissprot?ID: ??P05787/P05783Background:Cytokeratin?18?is a type?Icytokeratin.?It?is, together with?its filament?partner cytokeratin?8,?perhaps the?most?commonly?found?products of the?intermediate filament gene family.In some epithelial cell types, cytokeratin?8?and?cytokeratin?18?are?the?sole?keratins?present.?The?classical?example?is?the?liver,?with cytokeratin 8/cytokeratin?18?representing the characteristic and?only?keratin?pair?of?normal?hepatocytes.?The?same?istrue for other?highly specialized?parenchymatous epithelia such?asacinar?cells?of the?pancreas,?proximal?tubular?epithelialcells of the?kidney, and certain endocrine?cells?such?as?pancreatic?islet?cells.?Furthermore,?cytokeratin?8/cytokeratin?18?occur?together?with?other?keratins—in?various?pseudostratified?(e.g.?respiratory) and?complex?(e.g.?glandular)?epithelia?and?in?the ??urothelium;?in these composite epithelial tissues, cytokeratin?8?and?cytokeratin18?are?often?most?prominent?in the?lumen-lining cells.?Even?in?non-keratinizing stratified squamous epithelia,?cytokeratin?8?and?cytokeratin?18?may?be focally?expressed?in the?basal cell?layer, together with cytokeratin?19?and the?constitutive?stratified-epithelial?keratins.In?regard to?malignant tumors, cytokeratin 8 and?cytokeratin?18?are?expressed?in?most?carcinomas?except?for?some?differentiated squamous cell carcinomas. Therefore, cytokeratin?8?and?cytokeratin?18?antibody?strongly?stain?most??adenocarcinomas,?hepatocellular carcinomas,?renal cell carcinomas, and?neuroendocrine?carcinomas.Subcellular?location:CytoplasmRecommended?method:Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.Immunogen:Synthetic?peptide corresponding?to cytokeratin 8residues?within?aa383‐C?terminal?of?cytokeratin?8?was used as?an?immunogen.Synthetic?peptide corresponding to cytokeratin?18residues?within?aa330-430 of?cytoketatin?18?was?used as an?immunogen.Storage?Buffer:PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.Storage conditions:-25°C?to?-18°CStorage instructions:Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.Recommended?Dilutions:IHC-P:?????1:50-1:100Background?References:1.?Wiedenmann?B,?et.al.?Proc?Natl?Acad?Sci?U?S?A.?1986?May;83(10):3500-4.2.?Quinn?B. Am?J?Surg?Pathol.?1998?May;22(5):550-6.Immunohistochemistry?(Formalin/PFA-fixedparaffin-embedded sections)?analysis of?colontissue?labelling?Cytokeratin????8&18 with?BP6005&BP6054.?Heat?mediated?antigenretrieval?was?performed????using Tris/EDTA?buffer?pH?9.0 HKZ150268_BP6005&BP6054_Cytokeratin 8&18下載 暫無 說明文檔下載說明書.pdf 上一篇: Cytokeratin 5&6兔單克隆抗體Cocktail下一篇: Caldesmon鼠單克隆抗體 推薦 動(dòng)物番紅固綠染色液 2023年7月13日 1358 【主要用途】 動(dòng)物番紅固綠染色液,石蠟切片技術(shù)里用于觀察骨組織的形態(tài)結(jié)構(gòu)。 【產(chǎn)品簡(jiǎn)介】 番紅 O 是一種可結(jié)合多陰離子的陽... 查看全文 ECL Basic(基本型) 2024年10月24日 1349 暫無 查看全文 Glucagon兔單克隆抗體 2024年5月23日 913 暫無 查看全文 GAP43兔多克隆抗體 2024年10月11日 1114 暫無 查看全文 您好!請(qǐng)登錄 點(diǎn)擊取消回復(fù) 請(qǐng)登錄后評(píng)論 點(diǎn)擊這里取消回復(fù)。
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