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Androgen Receptor兔單克隆抗體

Androgen Receptor兔單克隆抗體

  • 價(jià)格￥1400
  • 規(guī)格100ul
  • 貨號(hào)HKZ150245
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150245Androgen Receptor兔單克隆抗體100ul支1400
Androgen?Receptor
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50122?Clone# ?BP6126
Predicted?Molecular Wt:
99kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P10275
Background:
Androgen?Receptor?is a?member of the superfamily of?ligand?responsive transcription?regulators. The?androgen?receptor
functions?in the?nucleus where?it?is?believed to act as?a transcriptional?regulator?mediating?the?action?of?male?sex?hormones.??The androgen?receptor?has wide distribution and?can?be demonstrated?by?immunohistochemistry?in?several?tissues?including
prostate, skin, and oral?mucosa. Androgen?receptor?has?been?reported?in?a?diverse?range?of?human tumors?including?osteosarcoma, and?in?prostatic carcinoma androgen?receptor expression?may?be?of?clinical?relevance.
Androgen?Receptor?is?recommended for the detection of specific?antigens?of?interest?in?normal?and?neoplastic tissues,?as?an?adjunct to conventional?histopathology?using?non-immunologic?histochemical stains.
Subcellular?location:
Nucleus
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to?residues within?aa1-100 of?Androgen?Receptor?was?used?as?an
immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Siu?MK??et?al.?Oncogenesis?5:e282?(2016).
2. ?Urbinati?G??et?al.?Mol?Ther?Nucleic?Acids?5:e301?(2016).
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections)?analysis of
prostate?labelling
Androgen?Receptor with?BP6126.?Heat?mediated ??antigen?retrieval was
performed?using
Tris/EDTA?buffer?pH?9.0.

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