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AMACR兔單克隆抗體

AMACR兔單克隆抗體

  • 價(jià)格¥1000
  • 規(guī)格100ul
  • 貨號(hào)HKZ150233
  • 單位
  • 品牌HaoKebio

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HaoKebioHKZ150233AMACR兔單克隆抗體100ul1000
AMACR
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50110?Clone# ?BP6115
Predicted?Molecular Wt:
42kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID:??Q9UHK6
Background:
Alpha-methylacyl-CoA?racemase?(AMACR), also?known asp504s,?is a?mitochondrial and?peroxisomal?enzyme that?is?involved?in?bile acid?biosynthesis and?beta-oxidation of?branched-chain fatty acids.
AMACR?is essential?in?lipid?metabolism, and?is expressed?in?normal?liver?(hepatocytes),?kidney?(tubular epithelial?cells)?and?gall
bladder?(epithelial cells).?Expression?has also?been found?in?lung?(bronchial epithelial?cells)?and?colon?(colonic?surface?epithelium).
In?immunohistochemistry?(IHC), AMACR antibody?has?been shown to?be a?specific?marker?of?prostatic?adenocarcinoma.
Subcellular?location:
Cytoplasm
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Full-length?recombinant?human AMACR was?used as an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Schmitz?W., J.?Biochem.?231:815-822(1995).
2.?Ghosh?D.,?Berg?J.M. J. Am. Chem. Soc.?132:3973-?3979(2010).
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections)?analysis of?liver?labelling AMACR with
BP6115.?Heat?mediated antigen?retrieval?was
performed?using
Tris/EDTA?buffer?pH?9.0.

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