一抗 抗體 試劑 MUC1兔單克隆抗體一抗 抗體 試劑 價(jià)格¥600規(guī)格100ul貨號HKZ150152單位支品牌HaoKebio QQ53383090 咨詢購買 產(chǎn)品介紹產(chǎn)品參數(shù)資料下載 品牌商品編碼商品名稱規(guī)格單位單價(jià)HaoKebioHKZ150152MUC1兔單克隆抗體100ul支600MUC?1Recombinant?Rabbit?Monoclonal Antibody?Product?DatasheetCatalog# ?BX50029?Clone# ?BP6034Predicted?Molecular Wt:122kDaPurity: ??ProA?affinity?purified?IgGSpecies Cross-reactivity:HumanForm: ??LiquidApplications:IHC-PSwissprot?ID: ??P15941?Background:MUC1?(Mucin?1)?is a transmembrane glycoprotein that?protects epithelial?cells?from?injury?caused?by?external?stimuli.?In????addition to this?role,?MUC1?is?involved?in cell-cell adhesion,?proliferation,?motility,?invasion and?survival.?In?epithelial?cells,?MUC1 expression?is?regulated?by?binding of TNFα to TNFR1 and?activation?of the?NFκB?pathway.?MUC1?is?present?in a variety of glandular?(secretory) epithelia?such?as?breast,?eccrine?and?apocrine?glands,?and?pancreas,whereas?little or?no?MUC1?is expressed?in the gastrointestinal epithelium,?endocervical?epithelium,?and?prostate?glands. The???immunoreactivity?is?usually?limited to apical cell?membranes,?but a?staining?of the?Golgi?zone?may?also?be?seen.?MUC1?can?be?demonstrated?in?most types of adenocarcinomas derived from secretory?epithelia.?In?well-differentiated?carcinomas,?thestaining?is?mostly?limited to?(apical) cell?membranes while?in the?less differentiated carcinomas,a?cytoplasmic?staining?is?seen?with?loss of staining?polarity?in the?membranes.?MUC1 was?used to?recognize epithelial differentiation when?cytokeratin was?difficult?to?visualize.?In?the?classification?ofhaematolymphoid?neoplasms, a?positive?MUC1?reaction?may?be an aid?in the?identification?of diffuse?large?B-cell?lymphoma,?plasma cell?neoplasms and?nodular?lymphocyte?predominant?Hodgkin’s?lymphoma.?Subcellular?location:Membrane/CytoplasmRecommended?method:Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.Immunogen:Synthetic?peptide corresponding to?MUC1?residues?within?aa1155-1255 of?MUC1 was?used?as?animmunogen.Storage?Buffer:PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.Storage conditions:-25°C?to?-18°CStorage instructions:Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.Recommended?Dilutions:IHC-P:?????1:100-1:200Immunohistochemistry(Formalin/PFA-fixedparaffin-embeddedsections?analysis of?human?ovarian cancer?tissuelabelling?MUC1 withBP6034.?Heat?mediated antigen?retrieval?wasperformed?using Tris/EDTA?buffer?pH?9.0Background?References:1.?Croce?MV, et.al, J?Histochem?Cytochem.?2003?Jun;51(6):781-8.2.??NakamoriS, et.al, Gastroenterology.?1994?Feb;106(2):353-61. HKZ150152_BP6034_MUC1下載 暫無 說明文檔下載說明書.pdf 上一篇: p40兔單克隆抗體下一篇: CD138兔單克隆抗體 推薦 熒光六標(biāo)信號放大試劑盒(石蠟切片適用) 2024年8月30日 2926 查看全文 磷酸化蛋白酶抑制劑 2023年7月11日 2488 操作說明 1. 使用前將本產(chǎn)品解凍、復(fù)溫。 2. 每100 μL裂解液中加入1 μL磷酸化蛋白酶抑制劑A液和1 μL磷酸化蛋白酶抑制劑B液,混勻... 查看全文 smooth muscle actin 兔多克隆抗體 2024年12月4日 1303 存儲說明: 以藍(lán)冰運(yùn)輸。收貨后,進(jìn)行分裝,并在-25°C 至-18°C 條件下儲 存。避免反復(fù)凍融。 推薦稀釋比: IHC-P: ... 查看全文 PD-1/CD279 兔多克隆即用型抗體 2024年12月2日 1260 存儲說明: 以藍(lán)冰運(yùn)輸。收貨后,進(jìn)行分裝,并在-25°C 至-18°C 條件下儲 存。避免反復(fù)凍融。 背景參考文獻(xiàn): 1. Helicobac... 查看全文 您好!請登錄 點(diǎn)擊取消回復(fù) 請登錄后評論 點(diǎn)擊這里取消回復(fù)。
磷酸化蛋白酶抑制劑 2023年7月11日 2488 操作說明 1. 使用前將本產(chǎn)品解凍、復(fù)溫。 2. 每100 μL裂解液中加入1 μL磷酸化蛋白酶抑制劑A液和1 μL磷酸化蛋白酶抑制劑B液,混勻... 查看全文
smooth muscle actin 兔多克隆抗體 2024年12月4日 1303 存儲說明: 以藍(lán)冰運(yùn)輸。收貨后,進(jìn)行分裝,并在-25°C 至-18°C 條件下儲 存。避免反復(fù)凍融。 推薦稀釋比: IHC-P: ... 查看全文
PD-1/CD279 兔多克隆即用型抗體 2024年12月2日 1260 存儲說明: 以藍(lán)冰運(yùn)輸。收貨后,進(jìn)行分裝,并在-25°C 至-18°C 條件下儲 存。避免反復(fù)凍融。 背景參考文獻(xiàn): 1. Helicobac... 查看全文
您好!請登錄