一抗 抗體 試劑 DOG1兔單克隆抗體一抗 抗體 試劑 價(jià)格¥1000規(guī)格100ul貨號(hào)HKZ150150單位支品牌HaoKebio QQ53383090 咨詢購(gòu)買 產(chǎn)品介紹產(chǎn)品參數(shù)資料下載 品牌商品編碼商品名稱規(guī)格單位單價(jià)HaoKebioHKZ150150DOG1兔單克隆抗體100ul支1000DOG1Recombinant?Rabbit?Monoclonal Antibody?Product?DatasheetCatalog# ?BX50027?Clone# ?BP6032Predicted?Molecular Wt:114kDaPurity: ??ProA?affinity?purified?IgGSpecies Cross-reactivity:HumanForm: ??LiquidApplications:IHC-PSwissprot?ID:??Q5XXA6Background:DOG1?is?a?calcium-dependent?chloride?channel?protein?that?is?encoded?by?a?gene?called?TMEM16A (TMEM16?FLJ10261,?ANO1,??ORAOV2, and?AOS2)?located?on?chromosome?11q13.?DOG1?has?many?significant?functions?such?as?regulation?of?the?cholinergic activity of gastrointestinal smooth?muscle and?regulation of?both?the?survival?and?proliferation?of?cells.DOG1?is detected?in gastrointestinal Cajal cells,?acinic?cells?in?salivary glands?(apical?membraneous?staining,?particularly?inserous cells),?pancreatic centroacinar cells,?liver cells,?and?epithelium?of?biliary tract,?breast,?stomach,?and?prostate.?More?than?90% of?all?gastrointestinal?stromal?tumors?(GISTs)?are?DOG1 positive,?irrespective?of?kit?mutation?and?CD117?positivity. Thestaining?pattern varies from cytoplasmic to?membranous, with?usually strong,?diffuse?intensity.DOG1?is an?important?marker?in the?identification of GIST together with?CD117,?slightly?more?sensitive?(particularly?in?gastricGIST without c-kit?mutation) and also?more?specific than?CD117.?DOG1?is?also?useful?in?the?classification?of?salivary?carcinomas,?and?pancreatic and?renal tumors.Subcellular?location:Membrane/CytoplasmRecommended?method:Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.Immunogen:Synthetic?peptide corresponding to?DOG1?residues?????within?aa1-100 of?DOG1 was?used?as?an?immunogen.Storage?Buffer:PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.Storage conditions:-25°C?to?-18°CStorage instructions:Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.Recommended?Dilutions:IHC-P:?????1:100-1:200Background?References:Immunohistochemistry(Formalin/PFA-fixedparaffin-embeddedsections analysis?of?GIST?????tissue?labelling?DOG1 with?BP6032.?Heat?mediatedantigen?retrieval?was?performed?usingTris/EDTA?buffer?pH?9.01.?Jung?SH, et.al, Gut?Liver.?2011 Jun;5(2):171-80.2. ?Bergmann?F, et.al,?Hum?Pathol.?2011 Jun;42(6):817-23. HKZ150150_BP6032_DOG1下載 暫無(wú) 說(shuō)明文檔下載說(shuō)明書.pdf 上一篇: PMEL17兔單克隆抗體下一篇: p40兔單克隆抗體 推薦 1M Tris-HCl(PH9.1)無(wú)菌 2024年9月30日 1396 暫無(wú) 查看全文 GRP75兔多克隆抗體 2024年10月11日 1049 暫無(wú) 查看全文 ROS1 重組兔單克隆抗體 2024年10月17日 986 背景參考文獻(xiàn): 1. Matsushime, H. et al. (1986) Mol Cell Biol 6, 3000-4. 2. Charest, A. et al. (2003) Genes Chromosomes Cancer 37, 58-71.... 查看全文 熒光單標(biāo)信號(hào)放大試劑盒(石蠟切片適用) 2024年6月19日 1410 查看全文 您好!請(qǐng)登錄 點(diǎn)擊取消回復(fù) 請(qǐng)登錄后評(píng)論 點(diǎn)擊這里取消回復(fù)。
ROS1 重組兔單克隆抗體 2024年10月17日 986 背景參考文獻(xiàn): 1. Matsushime, H. et al. (1986) Mol Cell Biol 6, 3000-4. 2. Charest, A. et al. (2003) Genes Chromosomes Cancer 37, 58-71.... 查看全文
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