\n
\n![\"PLA2R\u5154\u5355\u514b\u9686\u6297\u4f53\"\/](\"https:\/\/www.haokebio.com\/wp-content\/themes\/smartenterprise\/images\/loading.png\")
<\/a><\/div><\/div>
![\"PLA2R\u5154\u5355\u514b\u9686\u6297\u4f53\"\/](\"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241015160528479.png?imageView2\/0\/format\/webp\/q\/75\")
<\/a><\/div><\/div>\nPLA2R\u5154\u5355\u514b\u9686\u6297\u4f53<\/h1><\/div>
PLA2R\u5154\u5355\u514b\u9686\u6297\u4f53<\/h1><\/div><\/i>\u4e00\u6297<\/a> \u6297\u4f53<\/a> \u8bd5\u5242<\/a> <\/span><\/div><\/header>- \u4ef7\u683c<\/span>\u00a51000<\/span><\/li>
- \u89c4\u683c<\/span>100ul<\/span><\/li>
- \u8d27\u53f7<\/span>HKZ150430<\/span><\/li>
- \u5355\u4f4d<\/span>\u652f<\/span><\/li>
- \u54c1\u724c<\/span>HaoKebio<\/span><\/li><\/ul>\n\n\n\nQQ53383090 \u54a8\u8be2\u8d2d\u4e70<\/a><\/div>\n<\/div>\n\n\n\n
<\/p>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>
<\/div><\/div><\/section>\n\n\n\n<\/i>\u4ea7\u54c1\u4ecb\u7ecd<\/span><\/div><\/i>\u4ea7\u54c1\u53c2\u6570<\/span><\/div><\/i>\u8d44\u6599\u4e0b\u8f7d<\/span><\/div><\/div><\/div>\n\n\u54c1\u724c<\/strong><\/th> \u5546\u54c1\u7f16\u7801<\/strong><\/th> \u5546\u54c1\u540d\u79f0<\/strong><\/th> \u89c4\u683c<\/strong><\/th> \u5355\u4f4d<\/strong><\/th> \u5355\u4ef7<\/strong><\/th><\/tr> HaoKebio<\/th> HKZ150430<\/th> PLA2R\u5154\u5355\u514b\u9686\u6297\u4f53<\/th> 100ul<\/th> \u652f<\/th> 1000<\/th><\/tr><\/tbody><\/table>PLA2R<\/strong>
Recombinant\u00a0Rabbit\u00a0Monoclonal Antibody Product\u00a0Datasheet<\/strong>
Catalog#\u00a0<\/strong>BX50307 Clone#\u00a0<\/strong>BP6284
Predicted\u00a0Molecular Wt:<\/strong>
169kDa
Purity:\u00a0\u00a0<\/strong>ProA affinity\u00a0purified\u00a0IgG
Species Cross-reactivity:<\/strong>
Human
Form:\u00a0\u00a0<\/strong>Liquid
Applications:<\/strong>
IHC-P
Swissprot\u00a0ID:\u00a0\u00a0<\/strong>Q13018
Background:<\/strong>
M-type\u00a0phospholipase\u00a0A2\u00a0receptor(PLA2R) , acts\u00a0as\u00a0a\u00a0receptor\u00a0for\u00a0phosholipase\u00a0sPLA2-IB\/PLA2G1B\u00a0but\u00a0not\u00a0sPLA2-
IIA\/PLA2G2A.\u00a0Binding\u00a0of\u00a0sPLA2-IB\/PLA2G1B\u00a0induces\u00a0various\u00a0effects\u00a0depending\u00a0on\u00a0the\u00a0cell\u00a0type,\u00a0such\u00a0as\u00a0activation\u00a0of\u00a0the \u00a0\u00a0\u00a0mitogen-activated\u00a0protein\u00a0kinase\u00a0(MAPK) cascade to\u00a0induce cell\u00a0proliferation, the\u00a0production of\u00a0lipid\u00a0mediators,\u00a0selective\u00a0release of arachidonic acid\u00a0in\u00a0bone\u00a0marrow-derived\u00a0mast cells.\u00a0In\u00a0podocytes,\u00a0binding\u00a0of sPLA2-IB\/PLA2G1B\u00a0can\u00a0regulate\u00a0\u00a0\u00a0\u00a0podocyte survival and glomerular\u00a0homeostasis.
PLA2R\u00a0is\u00a0highly\u00a0expressed\u00a0in\u00a0podocytes\u00a0in\u00a0human glomeruli,\u00a0also\u00a0expressed\u00a0in\u00a0pancreas,\u00a0amnion, choriodecidua\u00a0and\u00a0placenta.
PLA2R was\u00a0identified\u00a0as a\u00a0major target antigen\u00a0involved\u00a0in\u00a0idiopathic\u00a0membranous\u00a0nephropathy\u00a0in\u00a0adults.\u00a0Circulating
autoantibodies against\u00a0PLA2R were found\u00a0in\u00a070 to\u00a080% of\u00a0patients\u00a0with\u00a0idiopathic\u00a0membranous\u00a0nephropathy\u00a0.\u00a0It\u00a0has\u00a0been\u00a0suggested that the serum\u00a0level of\u00a0PLA2R autoantibody\u00a0could\u00a0be\u00a0used\u00a0for the\u00a0diagnosis\u00a0of\u00a0idiopathic\u00a0membranous
nephropathy\u00a0and for the\u00a0monitoring of\u00a0response to treatment.
Subcellular\u00a0location:<\/strong>
Membranous
Recommended\u00a0Method:<\/strong>
Heat\u00a0induced epitope\u00a0retrieval with Tris-EDTA\u00a0buffer\u00a0\u00a0\u00a0(pH\u00a09.0),\u00a0primary\u00a0antibody\u00a0incubate\u00a0at\u00a0RT\u00a0(18\u00b0C-25\u00b0C)\u00a0for\u00a030\u00a0minutes.
Immunogen:<\/strong>
Synthetic\u00a0peptide. This\u00a0information\u00a0is\u00a0proprietary to\u00a0Biolynx.
Storage\u00a0Buffer:<\/strong>
PBS\u00a059%, Sodium\u00a0azide\u00a00.01%,\u00a0Glycerol\u00a040%,\u00a0BSA 0.05%.
Storage Conditions:<\/strong>
-25\u00b0C\u00a0to\u00a0-18\u00b0C
Shipment\u00a0Instructions:<\/strong>
Shipped\u00a0on\u00a0blue\u00a0ice.\u00a0Upon\u00a0delivery\u00a0store\u00a0at\u00a0-25\u00b0C\u00a0to\u00a0–\u00a018\u00b0C. Avoid\u00a0freeze\u00a0\/ thaw\u00a0cycles.
Recommended\u00a0Dilution:<\/strong>
IHC-P:\u00a0\u00a0\u00a0\u00a0\u00a01:100-1:200
Background\u00a0References:<\/strong>
1.\u00a0Beck\u00a0LH\u00a0Jr,\u00a0et\u00a0al.\u00a0Kidney\u00a0Int\u00a077:765-770,\u00a02010.
2.\u00a0R.J. Glassock.Contrib\u00a0Nephrol,\u00a0181:131-142,2013.
Immunohistochemistry\u00a0(Formalin\/PFA-fixed\u00a0paraffin-embedded\u00a0sections) analysis of \u00a0human glomeruli\u00a0tissue\u00a0sections\u00a0labeling
PLA2R\u00a0with\u00a0BP6284.<\/figcaption><\/figure>\n\n\n\nHKZ150430_BP6284_PLA2R<\/a>\u4e0b\u8f7d<\/a><\/div>\n<\/div>\n\n\n\n<\/div>\n<\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":11194,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"themepark_post_bcolor":"#f5f5f5","themepark_post_width":"1022px","themepark_post_img":"","themepark_post_img_po":"left","themepark_post_img_re":false,"themepark_post_img_cover":false,"themepark_post_img_fixed":false,"themepark_post_hide_title":false,"themepark_post_main_b":"","themepark_post_main_p":100,"themepark_paddingblock":false,"footnotes":""},"categories":[101,99,98],"tags":[],"class_list":["post-6278","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-yk","category-kt","category-products"],"metadata":{"_wp_page_template":["default"],"_wpcom_metas":["a:1:{s:11:\"show_indent\";s:1:\"0\";}"],"views":["1113"],"_canshu":["a:5:{i:0;a:5:{s:5:\"title\";s:6:\"\u4ef7\u683c\";s:4:\"text\";s:6:\"\u00a51000\";s:2:\"f1\";i:16;s:2:\"f2\";s:7:\"#e21f2f\";s:2:\"f3\";b:1;}i:1;a:5:{s:5:\"title\";s:6:\"\u89c4\u683c\";s:4:\"text\";s:5:\"100ul\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";s:0:\"\";}i:2;a:5:{s:5:\"title\";s:6:\"\u8d27\u53f7\";s:4:\"text\";s:9:\"HKZ150430\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";s:0:\"\";}i:3;a:5:{s:5:\"title\";s:6:\"\u5355\u4f4d\";s:4:\"text\";s:3:\"\u652f\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";b:0;}i:4;a:5:{s:5:\"title\";s:6:\"\u54c1\u724c\";s:4:\"text\";s:8:\"HaoKebio\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";s:0:\"\";}}"],"catce":["sidebar-widgets4"],"_thumbnail_id":["11194"],"_dp_original":["6276"],"_edit_lock":["1732522322:2"],"_edit_last":["2"]},"medium_url":"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241015160528479.png","thumbnail_url":"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241015160528479-251x193.png","full_url":"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241015160528479.png","_links":{"self":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts\/6278"}],"collection":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/comments?post=6278"}],"version-history":[{"count":9,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts\/6278\/revisions"}],"predecessor-version":[{"id":12908,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts\/6278\/revisions\/12908"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/media\/11194"}],"wp:attachment":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/media?parent=6278"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/categories?post=6278"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/tags?post=6278"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
- \u4ef7\u683c<\/span>\u00a51000<\/span><\/li>
- \u89c4\u683c<\/span>100ul<\/span><\/li>
- \u8d27\u53f7<\/span>HKZ150430<\/span><\/li>
- \u5355\u4f4d<\/span>\u652f<\/span><\/li>
- \u54c1\u724c<\/span>HaoKebio<\/span><\/li><\/ul>\n\n\n\nQQ53383090 \u54a8\u8be2\u8d2d\u4e70<\/a><\/div>\n<\/div>\n\n\n\n
<\/p>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>
<\/div><\/div><\/section>\n\n\n\n<\/i>\u4ea7\u54c1\u4ecb\u7ecd<\/span><\/div><\/i>\u4ea7\u54c1\u53c2\u6570<\/span><\/div><\/i>\u8d44\u6599\u4e0b\u8f7d<\/span><\/div><\/div><\/div>\n\n\u54c1\u724c<\/strong><\/th> \u5546\u54c1\u7f16\u7801<\/strong><\/th> \u5546\u54c1\u540d\u79f0<\/strong><\/th> \u89c4\u683c<\/strong><\/th> \u5355\u4f4d<\/strong><\/th> \u5355\u4ef7<\/strong><\/th><\/tr> HaoKebio<\/th> HKZ150430<\/th> PLA2R\u5154\u5355\u514b\u9686\u6297\u4f53<\/th> 100ul<\/th> \u652f<\/th> 1000<\/th><\/tr><\/tbody><\/table> PLA2R<\/strong>
Recombinant\u00a0Rabbit\u00a0Monoclonal Antibody Product\u00a0Datasheet<\/strong>
Catalog#\u00a0<\/strong>BX50307 Clone#\u00a0<\/strong>BP6284
Predicted\u00a0Molecular Wt:<\/strong>
169kDa
Purity:\u00a0\u00a0<\/strong>ProA affinity\u00a0purified\u00a0IgG
Species Cross-reactivity:<\/strong>
Human
Form:\u00a0\u00a0<\/strong>Liquid
Applications:<\/strong>
IHC-P
Swissprot\u00a0ID:\u00a0\u00a0<\/strong>Q13018
Background:<\/strong>
M-type\u00a0phospholipase\u00a0A2\u00a0receptor(PLA2R) , acts\u00a0as\u00a0a\u00a0receptor\u00a0for\u00a0phosholipase\u00a0sPLA2-IB\/PLA2G1B\u00a0but\u00a0not\u00a0sPLA2-
IIA\/PLA2G2A.\u00a0Binding\u00a0of\u00a0sPLA2-IB\/PLA2G1B\u00a0induces\u00a0various\u00a0effects\u00a0depending\u00a0on\u00a0the\u00a0cell\u00a0type,\u00a0such\u00a0as\u00a0activation\u00a0of\u00a0the \u00a0\u00a0\u00a0mitogen-activated\u00a0protein\u00a0kinase\u00a0(MAPK) cascade to\u00a0induce cell\u00a0proliferation, the\u00a0production of\u00a0lipid\u00a0mediators,\u00a0selective\u00a0release of arachidonic acid\u00a0in\u00a0bone\u00a0marrow-derived\u00a0mast cells.\u00a0In\u00a0podocytes,\u00a0binding\u00a0of sPLA2-IB\/PLA2G1B\u00a0can\u00a0regulate\u00a0\u00a0\u00a0\u00a0podocyte survival and glomerular\u00a0homeostasis.
PLA2R\u00a0is\u00a0highly\u00a0expressed\u00a0in\u00a0podocytes\u00a0in\u00a0human glomeruli,\u00a0also\u00a0expressed\u00a0in\u00a0pancreas,\u00a0amnion, choriodecidua\u00a0and\u00a0placenta.
PLA2R was\u00a0identified\u00a0as a\u00a0major target antigen\u00a0involved\u00a0in\u00a0idiopathic\u00a0membranous\u00a0nephropathy\u00a0in\u00a0adults.\u00a0Circulating
autoantibodies against\u00a0PLA2R were found\u00a0in\u00a070 to\u00a080% of\u00a0patients\u00a0with\u00a0idiopathic\u00a0membranous\u00a0nephropathy\u00a0.\u00a0It\u00a0has\u00a0been\u00a0suggested that the serum\u00a0level of\u00a0PLA2R autoantibody\u00a0could\u00a0be\u00a0used\u00a0for the\u00a0diagnosis\u00a0of\u00a0idiopathic\u00a0membranous
nephropathy\u00a0and for the\u00a0monitoring of\u00a0response to treatment.
Subcellular\u00a0location:<\/strong>
Membranous
Recommended\u00a0Method:<\/strong>
Heat\u00a0induced epitope\u00a0retrieval with Tris-EDTA\u00a0buffer\u00a0\u00a0\u00a0(pH\u00a09.0),\u00a0primary\u00a0antibody\u00a0incubate\u00a0at\u00a0RT\u00a0(18\u00b0C-25\u00b0C)\u00a0for\u00a030\u00a0minutes.
Immunogen:<\/strong>
Synthetic\u00a0peptide. This\u00a0information\u00a0is\u00a0proprietary to\u00a0Biolynx.
Storage\u00a0Buffer:<\/strong>
PBS\u00a059%, Sodium\u00a0azide\u00a00.01%,\u00a0Glycerol\u00a040%,\u00a0BSA 0.05%.
Storage Conditions:<\/strong>
-25\u00b0C\u00a0to\u00a0-18\u00b0C
Shipment\u00a0Instructions:<\/strong>
Shipped\u00a0on\u00a0blue\u00a0ice.\u00a0Upon\u00a0delivery\u00a0store\u00a0at\u00a0-25\u00b0C\u00a0to\u00a0–\u00a018\u00b0C. Avoid\u00a0freeze\u00a0\/ thaw\u00a0cycles.
Recommended\u00a0Dilution:<\/strong>
IHC-P:\u00a0\u00a0\u00a0\u00a0\u00a01:100-1:200
Background\u00a0References:<\/strong>
1.\u00a0Beck\u00a0LH\u00a0Jr,\u00a0et\u00a0al.\u00a0Kidney\u00a0Int\u00a077:765-770,\u00a02010.
2.\u00a0R.J. Glassock.Contrib\u00a0Nephrol,\u00a0181:131-142,2013.
Immunohistochemistry\u00a0(Formalin\/PFA-fixed\u00a0paraffin-embedded\u00a0sections) analysis of \u00a0human glomeruli\u00a0tissue\u00a0sections\u00a0labeling
PLA2R\u00a0with\u00a0BP6284.<\/figcaption><\/figure>\n\n\n\nHKZ150430_BP6284_PLA2R<\/a>\u4e0b\u8f7d<\/a><\/div>\n<\/div>\n\n\n\n<\/div>\n<\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":11194,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"themepark_post_bcolor":"#f5f5f5","themepark_post_width":"1022px","themepark_post_img":"","themepark_post_img_po":"left","themepark_post_img_re":false,"themepark_post_img_cover":false,"themepark_post_img_fixed":false,"themepark_post_hide_title":false,"themepark_post_main_b":"","themepark_post_main_p":100,"themepark_paddingblock":false,"footnotes":""},"categories":[101,99,98],"tags":[],"class_list":["post-6278","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-yk","category-kt","category-products"],"metadata":{"_wp_page_template":["default"],"_wpcom_metas":["a:1:{s:11:\"show_indent\";s:1:\"0\";}"],"views":["1113"],"_canshu":["a:5:{i:0;a:5:{s:5:\"title\";s:6:\"\u4ef7\u683c\";s:4:\"text\";s:6:\"\u00a51000\";s:2:\"f1\";i:16;s:2:\"f2\";s:7:\"#e21f2f\";s:2:\"f3\";b:1;}i:1;a:5:{s:5:\"title\";s:6:\"\u89c4\u683c\";s:4:\"text\";s:5:\"100ul\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";s:0:\"\";}i:2;a:5:{s:5:\"title\";s:6:\"\u8d27\u53f7\";s:4:\"text\";s:9:\"HKZ150430\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";s:0:\"\";}i:3;a:5:{s:5:\"title\";s:6:\"\u5355\u4f4d\";s:4:\"text\";s:3:\"\u652f\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";b:0;}i:4;a:5:{s:5:\"title\";s:6:\"\u54c1\u724c\";s:4:\"text\";s:8:\"HaoKebio\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";s:0:\"\";}}"],"catce":["sidebar-widgets4"],"_thumbnail_id":["11194"],"_dp_original":["6276"],"_edit_lock":["1732522322:2"],"_edit_last":["2"]},"medium_url":"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241015160528479.png","thumbnail_url":"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241015160528479-251x193.png","full_url":"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241015160528479.png","_links":{"self":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts\/6278"}],"collection":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/comments?post=6278"}],"version-history":[{"count":9,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts\/6278\/revisions"}],"predecessor-version":[{"id":12908,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts\/6278\/revisions\/12908"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/media\/11194"}],"wp:attachment":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/media?parent=6278"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/categories?post=6278"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/tags?post=6278"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}