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\n![\"Calreticulin\u5154\u5355\u514b\u9686\u6297\u4f53\"\/](\"https:\/\/www.haokebio.com\/wp-content\/themes\/smartenterprise\/images\/loading.png\")
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![\"Calreticulin\u5154\u5355\u514b\u9686\u6297\u4f53\"\/](\"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241015154817749.png?imageView2\/0\/format\/webp\/q\/75\")
<\/a><\/div><\/div>\nCalreticulin\u5154\u5355\u514b\u9686\u6297\u4f53<\/h1><\/div>
Calreticulin\u5154\u5355\u514b\u9686\u6297\u4f53<\/h1><\/div><\/i>\u4e00\u6297<\/a> \u6297\u4f53<\/a> \u8bd5\u5242<\/a> <\/span><\/div><\/header>- \u4ef7\u683c<\/span>\u00a51000<\/span><\/li>
- \u89c4\u683c<\/span>100ul<\/span><\/li>
- \u8d27\u53f7<\/span>HKZ150425<\/span><\/li>
- \u5355\u4f4d<\/span>\u652f<\/span><\/li>
- \u54c1\u724c<\/span>HaoKebio<\/span><\/li><\/ul>\n\n\n\nQQ53383090 \u54a8\u8be2\u8d2d\u4e70<\/a><\/div>\n<\/div>\n\n\n\n
<\/p>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>
<\/div><\/div><\/section>\n\n\n\n<\/i>\u4ea7\u54c1\u4ecb\u7ecd<\/span><\/div><\/i>\u4ea7\u54c1\u53c2\u6570<\/span><\/div><\/i>\u8d44\u6599\u4e0b\u8f7d<\/span><\/div><\/div><\/div>\n\n\u54c1\u724c<\/strong><\/th> \u5546\u54c1\u7f16\u7801<\/strong><\/th> \u5546\u54c1\u540d\u79f0<\/strong><\/th> \u89c4\u683c<\/strong><\/th> \u5355\u4f4d<\/strong><\/th> \u5355\u4ef7<\/strong><\/th><\/tr> HaoKebio<\/th> HKZ150425<\/th> Calreticulin\u5154\u5355\u514b\u9686\u6297\u4f53<\/th> 100ul<\/th> \u652f<\/th> 1000<\/th><\/tr><\/tbody><\/table>Calreticulin<\/strong>
Recombinant\u00a0Rabbit\u00a0Monoclonal Antibody\u00a0Product\u00a0Datasheet<\/strong>
Catalog# \u00a0<\/strong>BX50302\u00a0Clone# \u00a0<\/strong>BP6279
Predicted\u00a0Molecular Wt:<\/strong>
48kDa
Purity: \u00a0\u00a0<\/strong>ProA\u00a0affinity\u00a0purified\u00a0IgG
Species Cross-reactivity:<\/strong>
Human
Form: \u00a0\u00a0<\/strong>Liquid
Applications:<\/strong>
IHC-P
Swissprot\u00a0ID: \u00a0\u00a0<\/strong>P27797
Background:<\/strong>
Calcium\u00a0is a\u00a0universal signaling\u00a0molecule\u00a0involved\u00a0in\u00a0many cellular functions, such\u00a0as\u00a0cell\u00a0motility,\u00a0metabolism,\u00a0protein
modification, et al.\u00a0Calcium\u00a0is stored\u00a0in the endoplasmic\u00a0reticulum\u00a0(ER),\u00a0where\u00a0it\u00a0is\u00a0buffered\u00a0by\u00a0calcium\u00a0binding\u00a0chaperones\u00a0such as calnexin and calreticulin.\u00a0Calreticulin\u00a0also functions\u00a0asan\u00a0ER\u00a0chaperone\u00a0that\u00a0ensures\u00a0proper\u00a0folding\u00a0and\u00a0quality
control of\u00a0newly synthesized glycoproteins.
Calreticulin\u00a0is expressed\u00a0in all\u00a0kinds of\u00a0normal tissues and\u00a0tumor\u00a0tissues.
Calreticulin\u00a0purified from tumor can stimulate the anti-tumor\u00a0immune\u00a0response\u00a0of the\u00a0body,\u00a0the\u00a0possible\u00a0mechanism\u00a0is\u00a0that\u00a0\u00a0\u00a0the calreticulin\u00a0molecule\u00a0binds to the tumor\u00a0antigen\u00a0polypeptide, and\u00a0in the\u00a0process\u00a0of\u00a0calreticulinto\u00a0the\u00a0cell\u00a0membrane,\u00a0the\u00a0tumor antigen\u00a0peptide\u00a0bound with\u00a0it\u00a0is\u00a0brought to the cell\u00a0membrane and\u00a0presented\u00a0to\u00a0the\u00a0antigen-presenting\u00a0cell,\u00a0thus
stimulating the anti-tumor\u00a0immune effect of the\u00a0body. Calreticulin\u00a0purified\u00a0from\u00a0tumor\u00a0can\u00a0stimulate\u00a0the\u00a0anti-tumor\u00a0immune\u00a0\u00a0response of the\u00a0body, the\u00a0possible\u00a0mechanism\u00a0is that the calreticulin\u00a0molecule\u00a0binds to the tumor\u00a0antigen\u00a0polypeptide,\u00a0and\u00a0in\u00a0the\u00a0process of calreticulinto the cell\u00a0membrane, the tumor\u00a0antigen\u00a0peptide\u00a0bound with\u00a0it\u00a0is\u00a0brought\u00a0to\u00a0the\u00a0cell\u00a0membrane
and\u00a0presented to the antigen-presenting cell, thus stimulating the\u00a0anti-tumor\u00a0immune\u00a0effect\u00a0of the\u00a0body.
Subcellular\u00a0location:<\/strong>
Cytoplasm
Recommended\u00a0Method:<\/strong>
Heat\u00a0induced epitope\u00a0retrieval with Tris-EDTA\u00a0buffer\u00a0\u00a0\u00a0(pH\u00a09.0),\u00a0primary\u00a0antibody\u00a0incubate\u00a0at\u00a0RT\u00a0(18\u00b0C-25\u00b0C)\u00a0for\u00a030\u00a0minutes.
Immunogen:<\/strong>
Synthetic\u00a0peptide. This\u00a0information\u00a0is\u00a0proprietary to\u00a0Biolynx.
Storage\u00a0Buffer:<\/strong>
PBS\u00a059%, Sodium\u00a0azide\u00a00.01%,\u00a0Glycerol\u00a040%,\u00a0BSA 0.05%.
Storage Conditions:<\/strong>
-25\u00b0C\u00a0to\u00a0-18\u00b0C
Shipment\u00a0Instructions:<\/strong>
Shipped\u00a0on\u00a0blue\u00a0ice.\u00a0Upon\u00a0delivery\u00a0store\u00a0at\u00a0-25\u00b0C\u00a0to\u00a0–\u00a018\u00b0C. Avoid\u00a0freeze\u00a0\/ thaw\u00a0cycles.
Recommended\u00a0Dilution:<\/strong>
IHC-P:\u00a0\u00a0\u00a0\u00a0\u00a01:100-1:200
Background\u00a0References:<\/strong>
1.\u00a0Groenendyk, J. et\u00a0al.\u00a0(2004)\u00a0Mol\u00a0Cells\u00a017,\u00a0383-9.
2.\u00a0Williams,\u00a0D.B.\u00a0(2006) J\u00a0Cell\u00a0Sci\u00a0119,\u00a0615-23.
Immunohistochemistry\u00a0(Formalin\/PFA-fixed\u00a0paraffin-embedded\u00a0sections)\u00a0analysis of \u00a0human\u00a0prostate\u00a0labelling Calreticulin\u00a0with\u00a0\u00a0\u00a0BP6279.<\/figcaption><\/figure>\n\n\n\nHKZ150425_BP6279_Calreticulin<\/a>\u4e0b\u8f7d<\/a><\/div>\n<\/div>\n\n\n\n\n<\/p>\n\n\n\n
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\n\u6682\u65e0<\/p>\n\n\n\n
\u8bf4\u660e\u6587\u6863\u4e0b\u8f7d<\/span><\/h3>- <\/i><\/a>\u8bf4\u660e\u4e66.pdf<\/span><\/a><\/li><\/ul><\/div><\/section>\n\n\n\n
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- \u4ef7\u683c<\/span>\u00a51000<\/span><\/li>
- \u89c4\u683c<\/span>100ul<\/span><\/li>
- \u8d27\u53f7<\/span>HKZ150425<\/span><\/li>
- \u5355\u4f4d<\/span>\u652f<\/span><\/li>
- \u54c1\u724c<\/span>HaoKebio<\/span><\/li><\/ul>\n\n\n\nQQ53383090 \u54a8\u8be2\u8d2d\u4e70<\/a><\/div>\n<\/div>\n\n\n\n
<\/p>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>
<\/div><\/div><\/section>\n\n\n\n<\/i>\u4ea7\u54c1\u4ecb\u7ecd<\/span><\/div><\/i>\u4ea7\u54c1\u53c2\u6570<\/span><\/div><\/i>\u8d44\u6599\u4e0b\u8f7d<\/span><\/div><\/div><\/div>\n\n\u54c1\u724c<\/strong><\/th> \u5546\u54c1\u7f16\u7801<\/strong><\/th> \u5546\u54c1\u540d\u79f0<\/strong><\/th> \u89c4\u683c<\/strong><\/th> \u5355\u4f4d<\/strong><\/th> \u5355\u4ef7<\/strong><\/th><\/tr> HaoKebio<\/th> HKZ150425<\/th> Calreticulin\u5154\u5355\u514b\u9686\u6297\u4f53<\/th> 100ul<\/th> \u652f<\/th> 1000<\/th><\/tr><\/tbody><\/table> Calreticulin<\/strong>
Recombinant\u00a0Rabbit\u00a0Monoclonal Antibody\u00a0Product\u00a0Datasheet<\/strong>
Catalog# \u00a0<\/strong>BX50302\u00a0Clone# \u00a0<\/strong>BP6279
Predicted\u00a0Molecular Wt:<\/strong>
48kDa
Purity: \u00a0\u00a0<\/strong>ProA\u00a0affinity\u00a0purified\u00a0IgG
Species Cross-reactivity:<\/strong>
Human
Form: \u00a0\u00a0<\/strong>Liquid
Applications:<\/strong>
IHC-P
Swissprot\u00a0ID: \u00a0\u00a0<\/strong>P27797
Background:<\/strong>
Calcium\u00a0is a\u00a0universal signaling\u00a0molecule\u00a0involved\u00a0in\u00a0many cellular functions, such\u00a0as\u00a0cell\u00a0motility,\u00a0metabolism,\u00a0protein
modification, et al.\u00a0Calcium\u00a0is stored\u00a0in the endoplasmic\u00a0reticulum\u00a0(ER),\u00a0where\u00a0it\u00a0is\u00a0buffered\u00a0by\u00a0calcium\u00a0binding\u00a0chaperones\u00a0such as calnexin and calreticulin.\u00a0Calreticulin\u00a0also functions\u00a0asan\u00a0ER\u00a0chaperone\u00a0that\u00a0ensures\u00a0proper\u00a0folding\u00a0and\u00a0quality
control of\u00a0newly synthesized glycoproteins.
Calreticulin\u00a0is expressed\u00a0in all\u00a0kinds of\u00a0normal tissues and\u00a0tumor\u00a0tissues.
Calreticulin\u00a0purified from tumor can stimulate the anti-tumor\u00a0immune\u00a0response\u00a0of the\u00a0body,\u00a0the\u00a0possible\u00a0mechanism\u00a0is\u00a0that\u00a0\u00a0\u00a0the calreticulin\u00a0molecule\u00a0binds to the tumor\u00a0antigen\u00a0polypeptide, and\u00a0in the\u00a0process\u00a0of\u00a0calreticulinto\u00a0the\u00a0cell\u00a0membrane,\u00a0the\u00a0tumor antigen\u00a0peptide\u00a0bound with\u00a0it\u00a0is\u00a0brought to the cell\u00a0membrane and\u00a0presented\u00a0to\u00a0the\u00a0antigen-presenting\u00a0cell,\u00a0thus
stimulating the anti-tumor\u00a0immune effect of the\u00a0body. Calreticulin\u00a0purified\u00a0from\u00a0tumor\u00a0can\u00a0stimulate\u00a0the\u00a0anti-tumor\u00a0immune\u00a0\u00a0response of the\u00a0body, the\u00a0possible\u00a0mechanism\u00a0is that the calreticulin\u00a0molecule\u00a0binds to the tumor\u00a0antigen\u00a0polypeptide,\u00a0and\u00a0in\u00a0the\u00a0process of calreticulinto the cell\u00a0membrane, the tumor\u00a0antigen\u00a0peptide\u00a0bound with\u00a0it\u00a0is\u00a0brought\u00a0to\u00a0the\u00a0cell\u00a0membrane
and\u00a0presented to the antigen-presenting cell, thus stimulating the\u00a0anti-tumor\u00a0immune\u00a0effect\u00a0of the\u00a0body.
Subcellular\u00a0location:<\/strong>
Cytoplasm
Recommended\u00a0Method:<\/strong>
Heat\u00a0induced epitope\u00a0retrieval with Tris-EDTA\u00a0buffer\u00a0\u00a0\u00a0(pH\u00a09.0),\u00a0primary\u00a0antibody\u00a0incubate\u00a0at\u00a0RT\u00a0(18\u00b0C-25\u00b0C)\u00a0for\u00a030\u00a0minutes.
Immunogen:<\/strong>
Synthetic\u00a0peptide. This\u00a0information\u00a0is\u00a0proprietary to\u00a0Biolynx.
Storage\u00a0Buffer:<\/strong>
PBS\u00a059%, Sodium\u00a0azide\u00a00.01%,\u00a0Glycerol\u00a040%,\u00a0BSA 0.05%.
Storage Conditions:<\/strong>
-25\u00b0C\u00a0to\u00a0-18\u00b0C
Shipment\u00a0Instructions:<\/strong>
Shipped\u00a0on\u00a0blue\u00a0ice.\u00a0Upon\u00a0delivery\u00a0store\u00a0at\u00a0-25\u00b0C\u00a0to\u00a0–\u00a018\u00b0C. Avoid\u00a0freeze\u00a0\/ thaw\u00a0cycles.
Recommended\u00a0Dilution:<\/strong>
IHC-P:\u00a0\u00a0\u00a0\u00a0\u00a01:100-1:200
Background\u00a0References:<\/strong>
1.\u00a0Groenendyk, J. et\u00a0al.\u00a0(2004)\u00a0Mol\u00a0Cells\u00a017,\u00a0383-9.
2.\u00a0Williams,\u00a0D.B.\u00a0(2006) J\u00a0Cell\u00a0Sci\u00a0119,\u00a0615-23.
Immunohistochemistry\u00a0(Formalin\/PFA-fixed\u00a0paraffin-embedded\u00a0sections)\u00a0analysis of \u00a0human\u00a0prostate\u00a0labelling Calreticulin\u00a0with\u00a0\u00a0\u00a0BP6279.<\/figcaption><\/figure>\n\n\n\nHKZ150425_BP6279_Calreticulin<\/a>\u4e0b\u8f7d<\/a><\/div>\n<\/div>\n\n\n\n\n<\/p>\n\n\n\n
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