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\u54c1\u724c<\/strong><\/th> | \u5546\u54c1\u7f16\u7801<\/strong><\/th> | \u5546\u54c1\u540d\u79f0<\/strong><\/th> | \u89c4\u683c<\/strong><\/th> | \u5355\u4f4d<\/strong><\/th> | \u5355\u4ef7<\/strong><\/th><\/tr> |
---|---|---|---|---|---|
HaoKebio<\/th> | HKZ150208<\/th> | CD5\u5154\u5355\u514b\u9686\u6297\u4f53<\/th> | 100ul<\/th> | \u652f<\/th> | 600<\/th><\/tr><\/tbody><\/table> Recombinant\u00a0Rabbit\u00a0Monoclonal Antibody\u00a0Product\u00a0Datasheet<\/strong> Catalog# \u00a0<\/strong>BX50085\u00a0Clone# \u00a0<\/strong>BP6090 Predicted\u00a0Molecular Wt:<\/strong> 55kDa Purity: \u00a0\u00a0<\/strong>ProA\u00a0affinity\u00a0purified\u00a0IgG Species Cross-reactivity:<\/strong> Human Form: \u00a0\u00a0<\/strong>Liquid Applications:<\/strong> IHC-P Swissprot\u00a0ID: \u00a0\u00a0<\/strong>P06127 Background:<\/strong> The CD5 antigen\u00a0is a transmembrane glycoprotein\u00a0expressed\u00a0on the\u00a0surface\u00a0of\u00a0practically\u00a0all\u00a0mature\u00a0human\u00a0T-cells\u00a0(about\u00a010% of\u00a0CD4+ T-cells\u00a0being\u00a0CD5\u00a0negative).\u00a0In\u00a0immature\u00a0(CD34+) T-cells, CD5\u00a0is\u00a0weakly\u00a0expressed, the\u00a0intensity\u00a0of\u00a0expression increaing\u00a0with\u00a0maturation.\u00a0CD5\u00a0is\u00a0also\u00a0expressed\u00a0in\u00a0a\u00a0small\u00a0subset\u00a0of\u00a0normal\u00a0human\u00a0B-cells\u00a0(20%\u00a0of\u00a0B-cells\u00a0in\u00a0the\u00a0peripheral blood, scattered cells\u00a0in the\u00a0lymph\u00a0node\u00a0mantle zone). The\u00a0CD5+\u00a0cells\u00a0are\u00a0probably\u00a0involved\u00a0in\u00a0B-T\u00a0interaction\u00a0and their\u00a0ligand\u00a0is\u00a0CD72 which\u00a0is\u00a0expressed\u00a0on\u00a0all\u00a0B\u00a0cells.\u00a0It\u00a0appears\u00a0that\u00a0CD5+\u00a0B-cells\u00a0on\u00a0activation\u00a0primarily\u00a0produce\u00a0IgM. They\u00a0also\u00a0produce \u00a0\u00a0\u00a0moreautoantibodies than\u00a0normal CD5\u00a0negative\u00a0B-cells. Thus, the CD5+\u00a0B-cell\u00a0population\u00a0is expanded\u00a0in\u00a0rheumatoid\u00a0arthrititis\u00a0and systemic\u00a0lupus erythematosus. The CD5 antibody\u00a0reacts with\u00a0CD5 expressed\u00a0on\u00a0B\u00a0and T\u00a0cells,\u00a0\u00a0and\u00a0may\u00a0be\u00a0a\u00a0useful\u00a0aid for\u00a0theclassification\u00a0of\u00a0B\u00a0and\u00a0T-cell malignancies. This\u00a0includes\u00a0B-cell\u00a0chronic\u00a0lymphoid\u00a0leukemia\u00a0(B-CLL),\u00a0B-cell\u00a0small\u00a0lymphocytic\u00a0lymphoma\u00a0(B-SLL),\u00a0mantle\u00a0cell lymphoma\u00a0(MCL) and T-cell\u00a0lymphoma and\u00a0leukemia.Subcellular\u00a0location:<\/strong> Cytomembrane Recommended\u00a0method:<\/strong> Heat\u00a0induced epitope\u00a0retrieval with Tris-EDTA\u00a0buffer\u00a0\u00a0\u00a0(pH\u00a09.0),\u00a0primary\u00a0antibody\u00a0incubate\u00a0at\u00a0RT\u00a0(18\u00b0C-25\u00b0C)\u00a0for\u00a030\u00a0minutes. Immunogen:<\/strong> Recombinant full\u00a0length\u00a0protein corresponding to Human\u00a0CD5\u00a0(extracellular). The\u00a0immunogen contains the\u00a0specific\u00a0extracellular\u00a0domain\u00a0of\u00a0huCD5\u00a0(D32-P372) Storage\u00a0Buffer:<\/strong> PBS\u00a059%, Sodium\u00a0azide\u00a00.01%,\u00a0Glycerol\u00a040%,\u00a0BSA 0.05%. Storage conditions:<\/strong> -25\u00b0C\u00a0to\u00a0-18\u00b0C Storage instructions:<\/strong> Shipped on\u00a0blue\u00a0ice.\u00a0Upon delivery,\u00a0aliquot,\u00a0and\u00a0store\u00a0at\u00a0-25\u00b0C\u00a0to\u00a0-18\u00b0C. Avoid\u00a0freeze\u00a0\/\u00a0thaw\u00a0cycles. Recommended\u00a0Dilutions:<\/strong> IHC-P:\u00a0\u00a0\u00a0\u00a0\u00a01:100-1:200 Background\u00a0References:<\/strong> 1.\u00a0Gloria\u00a0Soldevila, et\u00a0al. J\u00a0Leukoc\u00a0Biol.\u00a02019;1-14. 2.\u00a0\u00a0Manjun\u00a0Zhao,\u00a0Ningning\u00a0Duan,et\u00a0al. Autoimmunity.2019;1-9. Immunohistochemistry\u00a0(Formalin\/PFA-fixed paraffin-embedded sections analysis\u00a0of appendix tissue\u00a0labelling\u00a0CD5 with\u00a0BP6090.\u00a0Heat \u00a0\u00a0\u00a0mediated\u00a0antigen retrieval\u00a0was\u00a0performed\u00a0using Tris\/EDTA\u00a0buffer\u00a0\u00a0\u00a0\u00a0pH\u00a09.0<\/figcaption><\/figure>\n\n\n\n HKZ150208_BP6090_ CD5<\/a>\u4e0b\u8f7d<\/a><\/div>\n<\/div>\n\n\n\n \n <\/p>\n\n\n\n \n \n <\/p>\n<\/div>\n<\/div>\n\n\n\n <\/p>\n\n\n\n <\/p>\n\n\n\n <\/p>\n<\/div>\n\n\n\n \n \u6682\u65e0<\/p>\n\n\n\n \u8bf4\u660e\u6587\u6863\u4e0b\u8f7d<\/span><\/h3><\/div><\/section>\n\n\n\n <\/p>\n<\/div>\n<\/div><\/div> <\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":11389,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"themepark_post_bcolor":"#f5f5f5","themepark_post_width":"1022px","themepark_post_img":"","themepark_post_img_po":"left","themepark_post_img_re":false,"themepark_post_img_cover":false,"themepark_post_img_fixed":false,"themepark_post_hide_title":false,"themepark_post_main_b":"","themepark_post_main_p":100,"themepark_paddingblock":false,"footnotes":""},"categories":[101,99,98],"tags":[],"class_list":["post-5756","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-yk","category-kt","category-products"],"metadata":{"_wp_page_template":["default"],"_wpcom_metas":["a:1:{s:11:\"show_indent\";s:1:\"0\";}"],"views":["866"],"_canshu":["a:5:{i:0;a:5:{s:5:\"title\";s:6:\"\u4ef7\u683c\";s:4:\"text\";s:5:\"\u00a5600\";s:2:\"f1\";i:16;s:2:\"f2\";s:7:\"#e21f2f\";s:2:\"f3\";b:1;}i:1;a:5:{s:5:\"title\";s:6:\"\u89c4\u683c\";s:4:\"text\";s:5:\"100ul\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";s:0:\"\";}i:2;a:5:{s:5:\"title\";s:6:\"\u8d27\u53f7\";s:4:\"text\";s:9:\"HKZ150208\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";s:0:\"\";}i:3;a:5:{s:5:\"title\";s:6:\"\u5355\u4f4d\";s:4:\"text\";s:3:\"\u652f\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";b:0;}i:4;a:5:{s:5:\"title\";s:6:\"\u54c1\u724c\";s:4:\"text\";s:8:\"HaoKebio\";s:2:\"f1\";s:0:\"\";s:2:\"f2\";s:0:\"\";s:2:\"f3\";s:0:\"\";}}"],"catce":["sidebar-widgets4"],"_thumbnail_id":["11389"],"_dp_original":["5749"],"_edit_lock":["1732003176:2"],"_edit_last":["2"]},"medium_url":"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241016110838509.png","thumbnail_url":"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241016110838509-251x193.png","full_url":"https:\/\/www.haokebio.com\/wp-content\/uploads\/2024\/05\/20241016110838509.png","_links":{"self":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts\/5756"}],"collection":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/comments?post=5756"}],"version-history":[{"count":8,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts\/5756\/revisions"}],"predecessor-version":[{"id":12511,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/posts\/5756\/revisions\/12511"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/media\/11389"}],"wp:attachment":[{"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/media?parent=5756"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/categories?post=5756"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.haokebio.com\/wp-json\/wp\/v2\/tags?post=5756"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}} |