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CK5&6兔單克隆抗體

CK5&6兔單克隆抗體

  • 價格￥600
  • 規(guī)格100ul
  • 貨號HKZ150398
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150398CK5&6兔單克隆抗體100ul支600
CK5&6
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50275?Clone# ?BP6252
Predicted?Molecular Wt:
62/60kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P13647/P02538/P04259/P48668
Background:
Cytokeratin?5?is a?basic?protein that?is closely?related to cytokeratin?6. They?share?similar?tissue?distribution?and?are?found?in???various?proportions?in?many?non-keratinizing stratified squamous epithelia eg. tongue?mucosa,?as?well?as?in?basal?epithelia?of?trachea,?basal cells of epidermis,?hair follicles, sebaceous?and?sweat?glands?of?skin,?luminal?cells?of the?mammary?gland,?basal?cells of?prostate,?urothelium, vagina and endocervical?mucosa.
Cytokeratins 5 and?6 are also?expressed?in?basal?cell?epitheliomas,?squamous?cell?carcinomas?of?skin, tongue,?epiglottis?and?of?the?rectal-anal?region.?Point?mutations?in?the?cytokeratin?5 gene?at?locus?12q11-q13?can?cause?various?types?of?epidermolysis bullosa simplex.
Subcellular?location:
Cytoplasmic
Recommended?Method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide. This?information?is?proprietary to?Biolynx.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage Conditions:
-25°C?to?-18°C
Shipment?Instructions:
Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?-18?°C. Avoid?freeze?/ thaw?cycles.
Recommended?Dilution:
IHC-P:?????1:100-1:200
Background?References:
1. ?Mukhopadhyay?S., et.al. ?Am?J?Surg?Pathol.?2011 Jan;?35(1):15-25.
2. ??KargiA, Gurel?D., et.al. Appl?Immunohistochem?Mol Morphol.?2007?Dec;?15(4):415-20.
Immunohistochemistry?(Formalin/PFA-fixed?paraffin-????embedded?sections)?analysis of ?human cervical?cancer?labelling?CK5&6 with?BP6252

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