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BRG1兔單克隆抗體

BRG1兔單克隆抗體

  • 價格￥1800
  • 規(guī)格100ul
  • 貨號HKZ150347
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150347BRG1兔單克隆抗體100ul支1800
BRG1
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50224?Clone# ?BP6201
Predicted?Molecular Wt:
185kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P51532
Background:
Transcriptional coactivator cooperating with?nuclear?hormone?receptors to?potentiate transcriptional activation.?Component????of the CREST-BRG1 complex,a?multiprotein complex that?regulates?promoter activation?by?orchestrating?a?calcium-dependent?release of a?repressor complex and?a?recruitment?of an?activator?complex.?In?resting?neurons,?transcription?of the?c-FOS
promoter?is?inhibited?by?BRG1-dependent?recruitment of a?phospho-RB1-HDAC?repressor complex.?Upon calcium?influx,?RB1?is?dephosphorylated?by calcineurin, which?leads to?release of the?repressor complex.
Subcellular?location:
Nucleus
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Full?length?protein corresponding to?Human?BRG1.
?Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
Euskirchen?G., Auerbach?R.K., Snyder?M.J.?Biol. Chem.?287:30897-30905(2012)
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections)?analysis of
Human Colon?tissue
labelling?BRG1?with
BP6201.?Heat?mediated antigen?retrieval was
performed?using
Tris/EDTA?buffer?pH?9.0

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