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MUC2鼠單克隆抗體

MUC2鼠單克隆抗體

  • 價(jià)格￥600
  • 規(guī)格100ul
  • 貨號(hào)HKZ150295
  • 單位支
  • 品牌HaoKebio

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HaoKebioHKZ150295MUC2鼠單克隆抗體100ul支600
MUC2
Mouse?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50172?Clone#?CCP58
Predicted?Molecular Wt:
540kDa
Purity: ??ProG?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID:??Q02817
Background:
Mucin?2 glycoprotein?(MUC2)?is a?540?kDa glycoprotein?belonging to the superfamily?of?mucins.?Mucins?are?high?molecular
weight glycoproteins?produced?by epithelial cells and?can?be?divided?into two?families;?secretory?mucins?and?membrane
bound?mucins.?MUC2?is a?mucus-forming secreted?mucin found?in the cytoplasm?of goblet?cells?in?small?intestine,?colon,
bronchus and salivary glands.?MUC2 expression?has?been?noted?in?primary gastrointestinal?tract?tumors?of?colonic,?gastric?and?esophageal origin.?MUC2 expression?has also?been found?in goblet?cells?in?colorectal?carcinoma?metastatic?to?the?ovary,?but
not?in?primary?mucinous ovarian adenocarcinoma.
Subcellular?location:
Cytoplasm
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
A?29 amino?acids?synthetic?peptide?(MI-29)?containing one?repeat?unit?of?23 amino?acids?and?part?of?the?next repeat of four amino?acids?in the VNTR?(variable
number of tandem?repeats).
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Chaves?P, et?al.?Dis?Esophagus.?2005;?18:383-7.
2. ?Mino-Kenudson?M, et?al. Arch?Pathol?Lab?Med.?2007;?131:86-90.
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections)?analysis
of??human appendix
tissue?labelling?MUC2
with?CCP58.?Heat
mediated?antigen
retrieval was?performed?using Tris/EDTA?buffer????pH?9.0

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